Results 251 to 260 of about 369,120 (314)

A protein chaperone can stabilize the intein-containing precursor to indirectly promote protein splicing. [PDF]

Protein Sci
Smetana JS, Powell CR, Bagdadi N, Ariagno TM, Thomas H, Weinberger J, Gur E, Lennon CW.   +7 more
europepmc   +1 more source

TRIM28‐Derived Peptide Exerts Anti‐Tumor Roles by Stabilizing Tumor Suppressive BRD7 Protein in Multiple Cancers

Advanced Science, EarlyView.
An α‐helical peptide, TAB12, designed to mimic the TRIM28 binding interface, competitively disrupts the TRIM28‐BRD7 interaction, thereby blocking ubiquitin‐mediated degradation of the tumor suppressor BRD7. This stabilization unleashes potent anti‐tumor effects across multiple tumor types with a favorable safety profile, offering a feasible strategy ...
Qingqing Wei, Changning Xue, Mengna Li, Jianxia Wei, Lemei Zheng, Shipeng Chen, Yijie Wang, Yumei Duan, Yanwei Luo, Wei Xiong, Ming Zhou   +10 more
wiley   +1 more source

The accessory protein ORF3a hijacks the CLCC1 chloride channel to disrupt ER homeostasis in betacoronavirus pathogenesis. [PDF]

Cell Discov
Guo L, Huang B, Yu H, Xu Y, Wei L, Zheng J, Li Y, Wu D, Zhao P, Wu C, Tan W, Jia Y.   +11 more
europepmc   +1 more source

PRRSV suppresses ER-phagy through Nsp2- and Nsp5-mediated degradation of FAM134B. [PDF]

Front Cell Infect Microbiol
Wang J, Sun H, Liang Y, Luo D, Li R, Xing G, Qiao S, Chen XX.   +7 more
europepmc   +1 more source

Blue Flag, Red Flag

, 1988
openaire   +1 more source

ZEB2 SUMOylation in Cardiac Fibroblast Drives Post-Infarction Cardiac Remodeling through CtBP1-Associated repression of Nr4a1. [PDF]

iScience
Wang Y, Cheng S, Chen H, Yang Z, Wu X, Zong Q, Wang J, Jiang Y, Yu Y, Chen H, Xue Y, Zhao Q, Yang J, Wang D.   +13 more
europepmc   +1 more source

Correction to "POU2F1 Promotes Chemoresistance in Colorectal Cancer Cells via Attenuates the MDR2 Degradation Mediated by PPP1R11 Lactylation". [PDF]

Adv Sci (Weinh)
europepmc   +1 more source