Advanced Healthcare Materials, EarlyView.An RBC membrane camouflaged, cell‐penetrating peptides R8‐based drug delivery system is constructed to achieve a synergistic combination of natural compounds triptolide (TP) and celastrol (Cel), inducing tumor cell apoptosis, reducing tumor metastasis invasion and triggering autophagy disorder in breast cancer and liver cancer.
Qian Cheng +6 more
wiley +1 more source
Tehnički VjesnikThe article investigates the influence of geometric parameters of CVD cutting inserts on flank and crater wear during dry turning. Turning of AISI 316L stainless steel was performed with different values of approach angles, rake angles, clearance angles,
Djordje Vukelic +6 more
doaj +1 more source
Dendrimer Conjugates with PD‐L1‐Binding Peptides Enhance In Vivo Antitumor Immune Response
Advanced Healthcare Materials, EarlyView.In this paper, a novel nanoparticle scaffold composed of dendrimers conjugated with peptide‐based immune checkpoint inhibitors, enhancing drug delivery efficacy is introduced. By conjugating PD‐L1‐binding peptides to dendrimers, multivalent binding effects are harnessed, resulting in enhanced binding affinity, prolonged half‐life, and improved ...
DaWon Kim +11 more
wiley +1 more source
A Rare Diagnosis of Flank Pain in an Emergency Department as Wunderlich Syndrome: A Case Report
Eurasian Journal of Emergency Medicine, 2018 Wunderlich syndrome (WS) is an uncommon cause of flank pain wherein spontaneous bleeding occurs into the subcapsular and perirenal spaces of the kidney. İt is most commonly attributed to renal tumors, especially angiomyolipomas.
Gulsah Cikrikci İsik +3 more
doaj +1 more source
Nanobody‐Decorated Lipid Nanoparticles for Enhanced mRNA Delivery to Tumors In Vivo
Advanced Healthcare Materials, EarlyView.This study presents a targeted mRNA‐LNP platform engineered with anti‐PSMA nanobodies for prostate cancer therapy. Using different in vivo models, the authors demonstrate selective uptake and mRNA delivery in PSMA+ cancer cells. However, while targeting is enhanced, mRNA delivery efficacy is limited by tissue penetration, tumor necrosis, and immune ...
Pol Escudé Martinez de Castilla +16 more
wiley +1 more source
Canine recurrent flank alopecia: a synthesis of theory and practice [PDF]
, 2014 Canine recurrent flank alopecia is a non-inflammatory, non-scarring alopecia of unknown etiology and has a visually striking clinical presentation.
Daminet, Sylvie +3 more
core +2 more sources
Discussion: “Machinability of Nodular Cast Irons: Part I—Tool Forces and Flank Adhesion” (Ham, I., Hitomi, K., and Thuering, G. L., 1961, ASME J. Eng. Ind., 83, pp. 142–153) [PDF]
, 1961 William Pentland
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Safety Evaluation of Repeated Application of Polymeric Microarray Patches in Miniature Pigs
Advanced Healthcare Materials, EarlyView.This study demonstrates the safety of repeated application of three types of microarray patches (MAPs), hydrogelforming, dissolving, and implantable, over four weeks in miniature pigs. No adverse skin or systemic effects were observed, supporting the clinical potential of MAPs as safe and effective drug delivery platforms.
Qonita Kurnia Anjani +4 more
wiley +1 more source
Seasonality Effects on Consumers Preferences Over Quality Attributes of Different Beef Products
, 2019 Using discrete choice modelling, the study investigates 946 American consumers willingness-to-pay and preferences for diverse beef products. A novel experiment was used to elicit the number of beef products that each consumer would purchase. The range of
Ardeshiri, Ali +2 more
core +1 more source
Closure to “Discussions of ‘Machinability of Nodular Cast Irons: Part I—Tool Forces and Flank Adhesion’” (1961, ASME J. Eng. Ind., 83, pp. 153–154) [PDF]
, 1961 Inyong Ham +2 more
openalex +1 more source