Results 141 to 150 of about 152,357 (314)

EIF1AX Nucleolar Condensates Enhance Susceptibilities for the Management of Endometrial Cancer

Advanced Science, EarlyView.
This schematic illustrates the mechanism of a senolytic strategy in endometrial cancer. EIF1AX facilitates the incorporation of DDX21 into nucleolar condensates, an event that suppresses rDNA transcription and induces cellular senescence. The compound 2,5‐MeC exploits this pathway by promoting EIF1AX nucleolar translocation and condensate formation ...
Chengyu Lv, Zihang Lin, Jiandong Sun, Yuhong Ye, Qibin Wu, Liangzhi Cai, Dabin Liu, Pengming Sun, Shie Wang   +8 more
wiley   +1 more source

Laparoscopic Retrieval of Foreign Body in the Kidney: An Unusual Case Report and Literature Review. [PDF]

Case Rep Urol
Bedaiwi AK, Qarmush MM, Almajed E, Alshamrani KA, Almugharriq MM, Almomen MH, Bedaiwi KK.   +6 more
europepmc   +1 more source

TECTONICS OF NORTHERN FLANK OF DNIPER-DONETS AULACOGEN IN THE CONTEXT OF CONTINENTAL RIFTOGENESIS GENERAL REGULARITIES

, 2012
A.E. Лукин, O. G. TSHIOHA, T. S. GEIKO, Volodymyr Omelchenko   +3 more
openalex   +2 more sources

Hyperandrogenemia Induces Trophoblast Ferroptosis and Early Pregnancy Loss in Patients With PCOS via CMA‐Dependent FTH1 Degradation

Advanced Science, EarlyView.
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou, Weijie Yang, Na Liu, Qing Liu, Jiamin Jin, Chenqiong Zhao, Xiaoying Jin, Miao Gui, Haiyan Zhu, Songying Zhang, Yinli Zhang   +10 more
wiley   +1 more source

Femoral arterial embolism of an airgun pellet in a dog. [PDF]

J Vet Diagn Invest
Oren S, Viner T, Tabaran FA.
europepmc   +1 more source

A PCR method for introducing mutations into cloned DNA by joining an internal primer to a tagged flanking primer

, 1992
Jörg Stappert, Johann Wirsching, Rolf Kemler   +2 more
openalex   +2 more sources

Interactions of Antibody Drug Conjugate Anti‐Tubulin and Topoisomerase I Inhibitor Payloads with Radiotherapy to Potentiate Immunotherapy

Advanced Science, EarlyView.
Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance, Bryan S. Yung, Michael M. Allevato, Marcus M Cheng, Maria F. Camargo, Robert Saddawi‐Konefka, Kanika Dhawan, Ashwyn K. Sharma, Mahsa Mortaja, Sophie Bice, Daniel J. Scanderbeg, Diego Alvarado, Jyoti Mayadev, Ramez N. Eskander, Stephen R. Adams, Pippa F. Cosper, J. Silvio Gutkind, Sunil J. Advani   +17 more
wiley   +1 more source

Hydrothermal weakening and slope instability at Vulcano (Italy) analyzed using drones and in-situ strength measurements. [PDF]

Commun Earth Environ
De Jarnatt BF, Walter TR, Heap MJ, Müller D, Pisciotta AF.   +4 more
europepmc   +1 more source

Flank facilitation for isoluminant chromatic stimuli

, 2010
Pi‐Chun Huang, K. T. Mullen, Robert F. Hess   +2 more
openalex   +1 more source

Nanoscale Mapping of the Subcellular Glycosylation Landscape

Advanced Science, EarlyView.
Using multiplexed super‐resolution imaging with fluorophore‐labeled lectins, this study reports intracellular glycosylation at the nanoscale across organelles and synaptic specializations. Extending glycan analysis beyond the cell surface, Glyco‐STORM reveals distinct glycosylation nanodomains in the ER, Golgi, lysosomes, and synaptic sites.
Helene Gregoria Schroeter, Steffen Sass, Mike Heilemann, Thomas Kuner, Maja Klevanski   +4 more
wiley   +1 more source