Results 191 to 200 of about 330,691 (353)

Topoisomerase I Inhibition in ETV4‐overexpressed Non‐Small Cell Lung Cancer Promotes Replication and Transcription Mediated R‐Loop Accumulation and DNA Damage

Advanced Science, EarlyView.
The oncogenic ETS factor ETV4 exerts a pleiotropic control over DNA replication both in a transcription‐dependent and ‐independent fashion in NSCLC cells. High‐ETV4 expression leads to R‐loop formation and DNA damage in response to TOP1 inhibition.
Jiaxi Zhang, Yan Wang, Shanhu Cao, Shelly M. Xie, Bei Liu, Yimeng Li, Yuqi Hou, Xue Meng, Mingzhu Ruan, Di Bu, Jia Kang, Ruxin Li, Lei Lou, Juan Wang, Lingxiao Xing   +14 more
wiley   +1 more source

Protocol for investigating working memory modulation of visual signal processing in the monkey extrastriate cortex using local field potentials. [PDF]

STAR Protoc
Roshanaei M, Daliri MR, Bahmani Z, Clark K, Noudoost B.   +4 more
europepmc   +1 more source

Elderly Woman With Flank Pain [PDF]

Annals of Emergency Medicine, 2019
Chia-Wei Hong, Hsiu-Lung Fan, Shih-Hung Tsai, Sy-Jou Chen, Jen-Chun Wang   +4 more
openaire   +3 more sources

Tryptophan Metabolite Indole‐3‐Aldehyde Induces AhR and c‐MYC Degradation to Promote Tumor Immunogenicity

Advanced Science, EarlyView.
Tryptophan metabolite Indole‐3‐aldehyde (I3A) downregulates cytosolic AhR and p‐ERK/c‐MYC proteins, together enhancing STAT3 phosphorylation and tumor immunogenicity. Overexpression of the Trp metabolic enzyme interleukin‐4‐induced gene‐1 (IL4I1) in tumor cells increases intracellular levels of I3A and enhances tumor immunogenicity.
Lei Cui, Zining Wang, Zixuan Guo, Hongxia Zhang, Yongxiang Liu, Huanling Zhang, Huan Jin, Feifei Xu, Xiaojuan Wang, Chunyuan Xie, Hui Guo, Tiantian Wang, Yanxun Lin, Qi Zhao, Penghui Zhou, Jing Tan, Jin‐Xin Bei, Peng Huang, Jinyun Liu, Xiaojun Xia   +19 more
wiley   +1 more source

An Enlarging Mass Superimposed on a Giant Congenital Melanocytic Nevus: A Case Report and Review of Literature. [PDF]

Clin Case Rep
Al-Zubaidi N, Sayna S, Kani ZA, Gheisari M, Zahedi K.   +4 more
europepmc   +1 more source

Human terminal deoxyribonucleotidyltransferase: molecular cloning and structural analysis of the gene and 5' flanking region.

, 1988
Lela K. Riley, Jennifer Morrow, Mary Jo S. Danton, Mary Sue Colemán   +3 more
openalex   +1 more source

The 5'-flanking region of the gene encoding the large subunit of ribulose-1,5-bisphosphate carboxylase/oxygenase is crucial for growth of the cyanobacterium Synechococcus sp. strain PCC 7942 at the level of CO2 in air [PDF]

, 1989
Devorah Friedberg, Aaron Kaplan, R Larona Ariel, Martin Kessel, Julie Seijffers   +4 more
openalex   +1 more source

Unraveling the Role of MDK‐SDC4 Interaction in Pancreatic Cancer‐Associated New‐Onset Diabetes by Single‐Cell Transcriptomic Analysis

Advanced Science, EarlyView.
Midkine (MDK) is a mediator of the interaction between pancreatic cancer and beta cells. MDK, which originated from pancreatic ductal adenocarcinoma cells, exerted deleterious effects on paraneoplastic beta cells by binding to the SDC4 receptor on the beta cell surface and subsequently downregulating the Ras signaling pathway, thereby impairing insulin
Zengyu Feng, Jianyao Lou, Chuanshuai Lin, Haocheng Yu, Yuheng Tu, Jiali Gong, Xiawei Li, Yulian Wu   +7 more
wiley   +1 more source

Investigation of Meat Quality, Volatilome, and Fatty Acid Composition of Meat Parts from Liangshan Semi-Fine Wool Sheep. [PDF]

Vet Sci
Zhang R, Xu Y, Wang H, Bai T, Wang X, Liu D, Zhang Y, Zhang L, Zhang J.   +8 more
europepmc   +1 more source

Nucleotide sequence analysis of the spacer regions flanking the rat rRNA transcription unit and identification of repetitive dements

, 1986
Libert Yavachev, O.I. Georgiev, Э. А. Брага, T.A. Avdonina, A.E. Bogonxjlova, Victor B. Zhurkin, В. В. Носиков, A.A. Hadjiolov   +7 more
openalex   +2 more sources