Results 241 to 250 of about 327,861 (339)

Tubeless Percutaneous Nephrolithotomy in the Barts 'Flank-Free' Modified Supine Position with 24-Hour Discharge: A Single-Center Experience. [PDF]

Medicina (Kaunas)
Kiss Z, Drabik G, Murányi M, Nagy A, Goumas IK, Flaskó T.   +5 more
europepmc   +1 more source

Sequence organization of repetitive elements in the flanking regions of the chloroplast ribosomal unit ofChlamydomonas reinhardii

, 1985
Michel Schneider, Jean‐Luc Darlix, Jeanne M. Erickson, Jean‐David Rochaix   +3 more
openalex   +2 more sources

Inhibition of Phosphodiesterase 10A by MP‐10 Rescues Behavioral Deficits and Normalizes Microglial Morphology and Synaptic Pruning in A Mouse Model of FOXP1 Syndrome

Advanced Science, EarlyView.
We demonstrate that Foxp1± mice, modeling FOXP1 haploinsufficiency, exhibit behavioral deficits, striatal neuroinflammatory changes including altered microglial complexity and synaptic pruning, and markedly reduced Pde10a expression. Pde10a inhibition starting immediately after birth restores Foxp1± behavior, microglial morphology, and pruning ...
Henning Fröhlich, Jing Wang, Ferdinand Althammer, Tim Schubert, Nina Kluck, Valery Grinevich, Stefanie Schmitteckert, Christian P. Schaaf, Gudrun A. Rappold   +8 more
wiley   +1 more source

Metabolic engineering of Parageobacillus thermoglucosidasius for thermophilic production of 1-butanol. [PDF]

AMB Express
Doménech P, Pogrebnyakov I, Jensen SI, Driessen JLSP, Riisager A, Nielsen AT.   +5 more
europepmc   +1 more source

NSP7 Molecular Degrader Attenuates Coronaviral Infection Through the β‐TrCP1/FBXO5 Axis

Advanced Science, EarlyView.
Host E3 ligase FBXO5 as a key regulator that promotes K48‐linked ubiquitination and proteasomal degradation of SARS‐CoV‐2 NSP7, thereby suppressing viral replication. NSP7 ubiquitination is co‐regulated by β‐TrCP1 and TAF1. Small molecule BC24877 disrupts β‐TrCP1‐mediated degradation of FBXO5, stabilizing FBXO5 and enhancing NSP7 clearance ...
Yao Tong, Travis B. Lear, Ferhan Tuncer, John J. Villandre, Áine N. Boudreau, Bo Lin, Irene Alfaras, Jason R. Kennerdell, Daniel P. Camarco, Mads B. Larsen, Yun Hua, Yanwen Chen, Meigin E. Chandler, Ricardo Pineda, Simon M. Barratt‐Boyes, John W. Evankovich, Toren Finkel, Yuan Liu, Bill B. Chen   +18 more
wiley   +1 more source

Comparative Analysis of the Dimensional Accuracy and Surface Characteristics of Gears Manufactured Using the 3D Printing (DMLS) Technique from 1.2709 Steel. [PDF]

Materials (Basel)
Sawicki J, Stachurski W, Kuryło P, Tertel E, Januszewicz B, Brancewicz-Steinmetz E, Bednarek A.   +6 more
europepmc   +1 more source

Gradient Solvent Replacement‐Mediated Formation of High‐Strength Hydrogel‐Forming Microneedle for Long‐Term Drug Delivery

Advanced Science, EarlyView.
A high‐strength pH‐responsive hydrogel‐forming microneedle integrates gradient solvent replacement to enhance the mechanical properties of the acrylonitrile‐acrylic acid copolymer network, ensuring robust transdermal penetration and long‐term drug release.
Hui Li, Fengzhen Meng, Chengwei Hu, Zhiyun Wu, Liuzhi Hao, Caijun Sun, Lijing Fang, Fan Pan, Shaoquan Bian, Huipeng Li, Mingjun Li, Bo Liu, Xiaoli Zhao   +12 more
wiley   +1 more source

Transcriptomic characterization of transitioning cell types in the skin of Atlantic salmon. [PDF]

BMC Biol
Ruiz Daniels R, Salisbury SJ, Sveen L, Villamayor PR, Taylor RS, Vaadal M, Tengs T, Krasnov A, Monaghan SJ, Ballantyne M, Penaloza C, Fast MD, Bron JE, Houston R, Robinson N, Robledo D.   +15 more
europepmc   +1 more source

Identification of an enhancer-like element in the 5′ flanking region of the rat apolipoprotein A-I gene

, 1988
Yu‐Sheng Chao, Xiaohua Ding, Peihua Dai, Tsuei-Ju Wu, Te‐Cheng Pan, Qian‐Lin Hao, Y. Tingting   +6 more
openalex   +1 more source

Gastrula‐Premarked Posterior Enhancer Primes Posterior Tissue Development Through Cross‐Talk with TGF‐β Signaling Pathway

Advanced Science, EarlyView.
A gastrula‐premarked enhancer within the first intron of Cdx2 governs posterior embryonic development via both regulating Cdx2 expression in cis and coordinating TGF‐β signaling in trans to ensure proper posterior body development. Functional rescue in gastruloids reveals a Cdx2‐independent pathway, highlighting p‐Enh‐eRNA as key epigenetic ...
Yingying Chen, Fengxiang Tan, Qing Fang, Lin Zhang, Jiaoyang Liao, Penglei Shen, Yun Qian, Mingzhu Wen, Rui Song, Yonggao Fu, He Jax Xu, Ran Wang, Cheng Li, Zhen Shao, Jinsong Li, Naihe Jing, Xianfa Yang   +16 more
wiley   +1 more source