Results 261 to 270 of about 330,691 (353)
Histone Demethylase UTX Suppresses Tumor Cell Proliferation by Regulating Stress Granules
These findings indicate that cytoplasmic UTX forms puncta and co‐localizes in stress granules (SGs) upon various stresses. UTX TPR‐domain‐dependently and demethylase‐activity‐independently destabilize SGs by binding G3BP1, the SG hub protein, to disrupt SG network, thus affects tumorigenesis.
Xikai Liu+17 more
wiley +1 more source
Progastrin Promotes Colorectal Cancer Stem Cell‐Like Properties via the Receptor PZR
The tumor microenvironment supports colorectal cancer (CRC) progression by maintaining cancer stem cells (CSCs) through progastrin (PG). This study identifies Protein Zero‐Related protein (PZR) as an essential receptor for PG activity, promoting CSC‐like signaling via SHP2/SRC/β‐catenin.
Julie Nguyen+22 more
wiley +1 more source
Retroperitoneal hydatid cyst in an Arab pediatric patient; diagnostic challenges and surgical management: a case report and review of literature. [PDF]
Haymoun D+3 more
europepmc +1 more source
The NLR protein PibH8 interacts with phenylalanine ammonia‐lyase OsPAL1 and E3 ubiquitin ligase OsFBK16. Through competitive binding, PibH8 weakens the interaction between OsFBK16 and OsPAL1, thereby reducing the degradation of OsPAL1 by OsFBK16. The Hap1 allele of PibH8 exhibits a higher expression level than Hap2, thus accumulating more PibH8 protein,
Denghao Xiang+17 more
wiley +1 more source
Evaluating the theranostic potential of ferumoxytol when combined with radiotherapy in a mammary dual tumor mouse model. [PDF]
Chang DY, Speth JP, Scarpelli ML.
europepmc +1 more source