Results 51 to 60 of about 327,861 (339)

Rate of convergence of attractors of reaction-diffusion equations with nonlinear boundary conditions

open access: yes, 2020
This paper we study the rate of convergence of the asymptotic dynamics of reaction-diffusion equations with nonlinear Robin boundary conditions. We show how the rate of convergence of the global attractors can be affected by the variation of the ...
Bezerra, Flank David Moraes   +1 more
core  

Optimization and analysis of cutting parameters using cryogenic media in machining of high strength alloy steel [PDF]

open access: yes, 2013
In this research, liquid Argon is used as a cryogenic media to optimize the cutting parameters for evaluation of tool flank wear width of Tungsten Carbide Insert (CNMG 120404-WF 4215) while turning high strength alloy steel.
Ali, Liaqat   +5 more
core  

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

Facilitation from collinear flanks is cancelled by non-collinear flanks

open access: yesVision Research, 2000
Detection of a central Gabor pattern is facilitated by the presence of collinear flanking patterns. We find that this facilitation is greatly reduced when the collinear flanks are combined with non-collinear flanks to form a coherent surround. These results are unlikely to be explained by mechanisms that merely transduce local contrast in a nonlinear ...
Joshua A. Solomon, Michael J. Morgan
openaire   +3 more sources

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan   +10 more
wiley   +1 more source

Crustal structure and rift flank uplift of the Adare Trough, Antarctica [PDF]

open access: yes, 2005
The Adare Trough, located 100 km northeast of Cape Adare, Antarctica, represents the extinct third arm of a Tertiary spreading ridge between East and West Antarctica. It is characterized by pronounced asymmetric rift flanks elevated up to over 2 km above
Ashalatha   +36 more
core   +1 more source

Determination of Intrinsic Sodium in Grass-Fed Bonsmara (Bos taurus indicus) Meat

open access: yesApplied Sciences
There is a view that grass-fed beef has human health benefits coupled with better quality attributes. Yet, organic sodium in grass-fed beef remains elusive and overlooked in meat processing.
Elphus J. Mkhwebane   +3 more
doaj   +1 more source

The Eastern Flank

open access: yes, 2022
We now move to the next cluster of villages : Neura-o-Pequeno, Neura-O-Grande, Māndur or Dōṁgrī (the latter is actually an island on a hillock in the marshes of the Kumbhārjuvem canal that forms a part of the Māndur village), Āzōśī (Azossim) and Karmaḷi (Carambolim).
openaire   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

open access: yesMolecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen   +12 more
wiley   +1 more source

Oscilações na área do quadrado

open access: yesCQD Revista Eletrônica Paulista de Matemática
Neste artigo, discutimos como o conhecimento do c´alculo diferencial e integral pode auxiliar os  professores na elaborac¸˜ao de atividades para o ensino b´asico.
Flank David Morais Bezerra   +1 more
doaj   +1 more source

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