Results 61 to 70 of about 327,861 (339)
Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren +16 more
wiley +1 more source
Effect of load flank angle modifications on the structural integrity of buttress threaded connections [PDF]
, 2013 One of the main requirements of threaded & coupled connections used in oil-producing wells is the ability to resist high tensile loads. In order to ensure integrity under ever-increasing loads, the geometric parameters of the connection can be modified ...
De Baets, Patrick +4 more
core +1 more source
Necrotizing Fasciitis of the Paraspinous Muscles
Western Journal of Emergency Medicine, 2010 Necrotizing fasciitis (NF) is a rare and lethal soft tissue infection that requires urgent surgical intervention. It is most often found in the extremities occurring with precipitating trauma or in immunocompromised states.
Law, Denise, Dhingra, Kapil R
doaj
Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
Investigating the performance of TiN and TiAIN coatings on milling cutter used for machining bimetal steel strip [PDF]
, 2009 Surface engineering of cutting tools (single point or multipoint) through advanced coatings (e.g., TiN) has contributed towards considerable improvement of tool life, productivity and machining quality [1] by modifying the tool substrate.
Haider, Julfikar, Sarwar, Mohammed
core
Validation of flank-to-flank measurements for predicting boar weight
Kansas Agricultural Experiment Station Research Reports, 2006 Allometric relationships, in which linear body dimensions are expressed as a function of body weight, are commonly used in growth studies. Previous work at Kansas State University showed a positive correlation between flank-to-flank measurement and sow body weight.
J. Quackenbush +6 more
openaire +3 more sources
Molecular Oncology, EarlyView.Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho +11 more
wiley +1 more source
Seismic characteristics of sediment drifts: An example from the Agulhas Plateau, southwest Indian Ocean [PDF]
, 2001 Sediment drifts provide information on the palaeoceanographic development of a region. Additionally, they may represent hydrocarbon reservoirs. Because of this, sediment drift investigation has increased over the last few years. Nevertheless, a number of
Uenzelmann-Neben, Gabriele
core +1 more source
Applied Sciences, 2019 Modelling methods for the transient temperature field of wear land on the flank of end mills have been proposed to address the challenges of inaccurate prediction in the temperature field of end mills during the high-speed peripheral milling of Ti6Al4V ...
Jianbiao Du +6 more
doaj +1 more source