Results 61 to 70 of about 152,357 (314)

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source

Removing Homocoupling Defects in Alkoxy/Alkyl‐PBTTT Enhances Polymer:Fullerene Co‐Crystal Formation and Stability

Advanced Functional Materials, EarlyView.
PBTTT‐OR‐R, a C14‐alkoxy/alkyl‐PBTTT polymer derivative, is of substantial interest for optoelectronics due to its specific fullerene intercalation behavior and enhanced charge‐transfer absorption. Comparing this polymer with (S) and without (O) homocoupling defects reveals that PBTTT‐OR‐R(O) forms stable co‐crystals with PC61BM, while PBTTT‐OR‐R(S ...
Zhen Liu, Jochen Vanderspikken, Paola Mantegazza, Stefania Moro, Mouna Hamid, Sigurd Mertens, Niko Van den Brande, Laurence Lutsen, Vincent Lemaur, David Beljonne, Giovanni Costantini, Koen Vandewal, Bruno Van Mele, Wouter Maes, Bart Goderis   +14 more
wiley   +1 more source

Tooth Flank Mismatch Meshing Analysis for Spiral Bevel Gear Based on Tilt Cutting Method

Jixie chuandong, 2019
The analysis method of tooth flank mismatch meshing is studied for the spiral bevel gear of automobile drive axle. Firstly，the mathematical model of tilt cutting method is established，and the cradle angle is derived according to the meshing equation，so ...
Shaowu Nie, Sicheng Tang, Juhua Huang, Hua Zhang, Changfa Lai, Yong Xu   +5 more
doaj  

Effect of Variations in Tooth Flank Form Among Teeth on Gear Vibration and an Sensory Evaluation Method Using Potential Gear Noise

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2010
Since variations in tooth flank form among the teeth of a gear are one of the primary causes of noise and vibration in gear systems, the effects of these variations should be analyzed.
Edzrol Niza MOHAMAD, Masaharu KOMORI, Shigeki MATSUMURA, Chanat RATANASUMAWONG, Masanori YAMASHITA, Takushi NOMURA, Haruo HOUJOH, Aizoh KUBO   +7 more
doaj   +1 more source

Exploring Dipolar Dynamics and Ionic Transport in Metal‐Organic Frameworks: Experimental and Theoretical Insights

Advanced Functional Materials, EarlyView.
In this study, the interplay of dipolar dynamics and ionic charge transport in MOF compounds is investigated. Synthesizing the novel structure CFA‐25 with integrated freely rotating dipolar groups, local and macroscopic effects, including interactions with Cs cations are explored.
Ralph Freund, Arthur Schulz, Peter Lunkenheimer, Maryana Kraft, Thomas Bergler, Harald Oberhofer, Dirk Volkmer   +6 more
wiley   +1 more source

Effects of High Order Modification of Work Head Setting on Tooth Flank Form and Contact Zone of Spiral Bevel Gear

Jixie chuandong, 2017
Based on the generating theory of the pinion of spiral bevel gears and the relative motion theory,the tooth flank equation with the work head setting high order modification formula is established. According to the manufacturing parameters of the working
Huang Gang, Zhang Weiqing, Guo Xiaodong, Wang Ge, Wen Yikai   +4 more
doaj  

Enzyme‐Regulated Extended Swelling of Hydrogels for Dehiscence‐Less Tissue Expansions

Advanced Functional Materials, EarlyView.
An interpenetrating hydrogel network with swelling under regulation by enzymatic degradation (INSURED) is fabricated to avoid dehiscence. INSURED remains structurally intact post‐implantation, while HYAL injection enables control over the onset and rate of swelling.
Byung Ik Park, Dong‐yup Lee, Sungsoo Lim, JangHyuk Kim, Min‐Gyu Lee, Chang Seo Park, Hyeonuk Na, Yong Eun Cho, Yun Hyeok Lee, Junsang Doh, Jeong‐Yun Sun   +10 more
wiley   +1 more source

A Rare Diagnosis of Flank Pain in an Emergency Department as Wunderlich Syndrome: A Case Report

Eurasian Journal of Emergency Medicine, 2018
Wunderlich syndrome (WS) is an uncommon cause of flank pain wherein spontaneous bleeding occurs into the subcapsular and perirenal spaces of the kidney. İt is most commonly attributed to renal tumors, especially angiomyolipomas.
Gulsah Cikrikci İsik, Seda Dagar, Halit Aytar, Yunsur Cevik   +3 more
doaj   +1 more source

Biomimetic Iridescent Skin: Robust Prototissues Spontaneously Assembled from Photonic Protocells

Advanced Functional Materials, EarlyView.
Uniform nanoparticles are induced to form arrays (photonic crystals) in the cores of biopolymer capsules, endowing these ‘protocells’ with structural color. These protocells are then assembled into large self‐standing objects, i.e., prototissues, with robust mechanical properties as well as iridescent optical properties.
Medha Rath, Briahnah Streeter, Satyam Srivastava, Jemma Wood, William E. Bentley, Taylor J. Woehl, Srinivasa R. Raghavan   +6 more
wiley   +1 more source