Results 131 to 140 of about 33,938 (298)

Evolutionary divergence and functional insights into the heteromeric cis‐prenyltransferase of Paramecium tetraurelia

open access: yesThe FEBS Journal, EarlyView.
Heteromeric cis‐prenyltransferases (CPT) are indispensable for dolichol synthesis and protein N‐glycosylation in most eukaryotes. The catalytic subunits are strongly conserved throughout evolution, in contrast to the evolutionarily variable accessory subunits. The POC1 protein from Paramecium tetraurelia is the smallest identified CPT‐accessory subunit
Agnieszka Onysk   +8 more
wiley   +1 more source

Lock, relax, load, and shoot: a molecular perspective on Nedd4 regulation

open access: yesThe FEBS Journal, EarlyView.
Structural basis of inactive and active states of the Nedd4 HECT E3 ligase subfamily, following a ‘lock, relax, load, and shoot’ mechanism. In the locked, autoinhibited state, intramolecular domain interactions restrain the HECT domain. Relaxation releases these restraints, allowing loading of ubiquitin onto the catalytic cysteine, followed by the ...
Masa Janosev   +2 more
wiley   +1 more source

Fracture Mechanics-Based Modelling of Tool Wear in Machining Ti6Al4V Considering the Microstructure of Cemented Carbide Tools

open access: yesJournal of Machine Engineering
This study introduces a new wear model that can predict tool life in the milling process of Ti6Al4V using a cemented carbide tool. The model uses a finite element (FE) simulation to predict crack growth in the tool material microstructure.
Hossein Gohari   +3 more
doaj   +1 more source

Eco-efficient process based on conventional machining as an alternative technology to chemical milling of aeronautical metal skin panels [PDF]

open access: yes, 2019
El fresado químico es un proceso diseñado para la reducción de peso de pieles metálicas que, a pesar de los problemas medioambientales asociados, se utiliza en la industria aeronáutica desde los años 50.
Sol Illana, Irene del
core  

No Art on a Dead Planet: Political Iconoclasm as Climate Activism

open access: yesJournal of Applied Philosophy, EarlyView.
ABSTRACT A trend has recently emerged among climate activists of attacking artworks as a means of registering protest. I analyse this mode of protest, which I term political iconoclasm, and offer a novel partial defence of political iconoclasm as a protest strategy for environmental activists. I focus on Just Stop Oil's attack on van Gogh's Sunflowers.
Alice Madeleine Hilder Jarvis
wiley   +1 more source

Morphological and molecular evidence reveals a new species of Characidium from the Ucayali‐Urubamba Piedmont, Peru, and novel molecular clades are proposed within the genus

open access: yesJournal of Fish Biology, EarlyView.
Abstract A new species of Characidium is described from the Urubamba River basin, within the Ucayali‐Urubamba Piedmont ecoregion, Peru. The new species can be readily distinguished from all congeners, except Characidium cacah, Characidium chicoi, Characidium helmeri, Characidium mirim, Characidium nana, Characidium nupelia, Characidium sterbai ...
Leonardo Oliveira‐Silva   +6 more
wiley   +1 more source

Identification of influent factors on surface integrity in nickel-base superalloy drilling [PDF]

open access: yes, 2010
For the critical rotating components in aeronautical industry, the metallurgical quality achieved after machining conditions could determine their mechanical behaviour in fatigue. To guarantee this quality, the tools, materials and cutting conditions are
Baili, Maher   +4 more
core   +1 more source

A new endemic pearl cichlid of the ‘Geophagus’ brasiliensis (Cichliformes: Cichlidae) species group from the Piranga River, upper Doce River basin, southeastern Brazil

open access: yesJournal of Fish Biology, EarlyView.
Abstract A new species of pearl cichlid of the ‘Geophagus’ brasiliensis species group, endemic to the Piranga River, a major tributary of the upper Doce River basin in the state of Minas Gerais, southeastern Brazil, is herein described. The new species is delimited using an integrative approach, with molecular‐based species delimitation methods coupled
Cidimar E. de Assis   +7 more
wiley   +1 more source

PENGARUH KECEPATAN PEMAKANAN DAN WAKTU PEMBERIAN PENDINGIN TERHADAP TINGKAT KEAUSAN CUTTER END MILL HSS HASIL PEMESINAN CNC MILLING PADA BAJA ST 40 [PDF]

open access: yes, 2012
The purpose of this research was to determine the influence of feedrate variation, timing of cooling variation, and the interaction between feedrate and timing of cooling to rate wear HSS end mill cutter in machining result CNC milling with ST 40 steel.
Estriyanto, Yuyun   +2 more
core  

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