Results 111 to 120 of about 261,128 (338)

Rod‐Shaped Nanotherapeutics Alleviate Rheumatoid Arthritis by Precisely Disrupting Platelet‐Mediated Pathological Crosstalk via a Morphology‐Dependent Manner

Advanced Science, EarlyView.
Owing to the margination effect, rod‐shaped nanoparticles exhibit markedly enhanced co‐localization with endothelial‐adherent platelets (PLTs) under dynamic blood flow. When internalized by PLTs, rod‐shaped PNR@Res inhibit FAK and PI3K/AKT signaling in a morphology‐dependent manner, thereby disrupting their pathological crosstalk with various ...
Bin Zhang, Yuanyi Hua, Xin Wen, Zhumei Liao, Jianheng Ren, Yajun Weng, Qin Wang   +6 more
wiley   +1 more source

Clinical course and disease burden of patients with generalized pustular psoriasis in Portugal: a multicenter retrospective cohort study

Journal of Dermatological Treatment
Objectives Generalized pustular psoriasis (GPP) is a rare, life-threatening skin inflammatory disorder. This study aimed to describe the disease course, treatment strategies, and healthcare utilization among patients with GPP in Portugal.Methods This ...
Tiago Torres, Joana Antunes, Ana Brasileiro, João Alves, Diana Bernardo, José Ramos, Diogo Sousa, Cristina Castro, Ana Gusmão Palmeiro, André Aparício Martins, Joana Fazendeiro Matos, Bárbara Vieira Granja, Pedro Ponte, Gabriela Marques Pinto, Paula Quirino, Francisco Menezes Brandão, Laetitia Teixeira, Sofia Magina, Maria João Paiva Lopes, Hugo Oliveira, Paulo Varela, João Telles Sousa, Paulo Filipe, Rui Tavares Bello   +23 more
doaj   +1 more source

A new flare star member candidate in the Pleiades cluster

, 2011
We present a new flare star, which was discovered during our survey on a selected field at the edge of the Pleiades cluster. The field was observed in the period 2007 - 2010 with three different CCD-cameras at the University Observatory Jena with ...
Ambartsumyan, Ambartsumyan, Basri, Broeg, Eisenbeiss, Hambly, Haro, Hertzsprung, Johnson, Kenyon, Mirzoyan, Mugrauer, Mugrauer, Rebolo, Rebolo, Rieke, Röser, Schwartz, Siess, Skrutskie, Stauffer, Stauffer, Steele, van Leeuwen, Zapatero Osorio   +24 more
core   +1 more source

Loss‐Based Ensemble Generative Adversarial Network Model for Enhancing the Sperm Morphology Classification

Advanced Intelligent Systems, EarlyView.
A loss‐based ensemble generative adversarial network (GAN) framework is proposed to address mode collapse in sperm morphology classification. By integrating spatial augmentation and multiple GAN models, the study enhances synthetic data quality. The Shifted Window Transformer achieves 95.37% accuracy on the HuSHeM dataset, outperforming previous ...
Berke Cansiz, Hamza Osman Ilhan, Gorkem Serbes   +2 more
wiley   +1 more source

Parents' WhatsApp coping resources in the context of ongoing political conflicts: An ecological exploration

American Journal of Community Psychology, EarlyView.
Abstract Mobile technologies have become significant resources for crisis communication and social support in recent years. However, despite empirical evidence pointing to the centrality of these technologies for parenthood in everyday life, it is yet unknown how parents' coping resources play a role in the digital environment.
Daphna Yeshua‐Katz, Stav Shapira, Orna Braun‐Lewensohn   +2 more
wiley   +1 more source

Clinical features of flare in Japanese patients with new-onset SLE and risk factors for SLE flare in daily clinical practice: a single-center cohort study

Immunological Medicine
This study aimed to elucidate the clinical features, outcomes and risk factors of flares in patients with systemic lupus erythematosus (SLE). Data were collected from patients with newly diagnosed SLE at the Fukushima Medical University Hospital between ...
Shuzo Sato, Shuhei Yoshida, Yuya Sumichika, Kenji Saito, Haruki Matsumoto, Jumpei Temmoku, Yuya Fujita, Naoki Matsuoka, Tomoyuki Asano, Kiyoshi Migita   +9 more
doaj   +1 more source

G-BAND AND HARD X-RAY EMISSIONS OF THE 2006 DECEMBER 14 FLARE OBSERVED BYHINODE/SOT ANDRHESSI [PDF]

, 2010
Kyoko Watanabe, Säm Krucker, Hugh Hudson, Toshifumi Shimizu, Satoshi Masuda, Kiyoshi Ichimoto   +5 more
openalex   +1 more source

The Global Airways in Practice: Long‐term Effects of Mepolizumab With or Without FESS on Type 2 Inflammation in Patients With CRSwNP

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is a type 2 inflammatory disease often associated with asthma. The global airway hypothesis suggests bidirectional inflammatory interactions between upper and lower airways. Mepolizumab, an anti–IL‐5 therapy, treats conditions systemically, while functional endoscopic sinus surgery ...
Jens Tidemandsen, Vibeke Backer, Anne Sophie Homøe, Thomas H. L. Jensen, Kasper Aanæs, Howraman Meteran, Morten Hostrup, Lukas Moesgaard, Christiane Haase, Peter G. Gibson   +9 more
wiley   +1 more source

RETRACTED: Near-cure in patients with Gadolinium deposition disease undergoing intravenous DTPA chelation

Frontiers in Toxicology
PurposeTo demonstrate and evaluate factors contributing to near-cures in patients with Gadolinium Deposition Disease (GDD) undergoing intravenous (IV) DTPA chelation.MethodsPatients who had undergone or are currently undergoing DTPA chelation for GDD ...
Richard C. Semelka, Miguel Ramalho
doaj   +1 more source

Discovery of the Sub-second Linearly Polarized Spikes of Synchrotron Origin in the UV Ceti Giant Optical Flare [PDF]

, 2017
G. Beskin, S. Karpov, V. Plokhotnichenko, A. Stepanov, Yu. Tsap   +4 more
openalex   +1 more source