Results 81 to 90 of about 261,128 (338)

Response to Allopurinol and Febuxostat According to the Fractional Excretion of Urate in Men With Gout

open access: yesArthritis Care &Research, EarlyView.
Objective Body mass index (BMI), glomerular filtration rate (GFR), and pretreatment urate levels have been reported to influence the urate‐lowering response to allopurinol. We investigated whether the fractional excretion of uric acid (FEUA) also modulates this response and relates to oxypurinol concentrations.
Pascal Richette   +13 more
wiley   +1 more source

Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Belimumab in Pediatric Patients with Systemic Lupus Erythematosus: A Multicenter, Open‐Label Trial

open access: yesArthritis Care &Research, Accepted Article.
Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; NCT04179032) used three‐weight‐band ...
Hermine I. Brunner   +14 more
wiley   +1 more source

Particle Acceleration Driven by Null Electromagnetic Fields Near a Kerr Black Hole

open access: yesUniverse, 2020
Short timescale variability is often associated with a black hole system. The consequence of an electromagnetic outflow suddenly generated near a Kerr black hole is considered assuming that it is described by a solution of a force-free field with a null ...
Yasufumi Kojima, Yuto Kimura
doaj   +1 more source

Validation of the SMOS Mission for Space Weather Operations: The Potential of Near Real‐Time Solar Observation at 1.4 GHz

open access: yesSpace Weather, 2021
Soil Moisture and Ocean Salinity (SMOS) is an ESA mission observing Earth at 1.4 GHz with full polarimetry. SMOS images are affected by a noise of solar origin produced by the Sun appearing in the antenna's field of view.
M. Flores‐Soriano   +2 more
doaj   +1 more source

Probing Particle Acceleration through Gamma-ray Solar Flare Observations [PDF]

open access: green, 2021
M. Pesce-Rollins   +3 more
openalex   +1 more source

A Flare of AE Aquarii Observed with XMM-Newton

open access: yes, 2006
We present the results of analyzing the XMM-Newton data obtained in 2001 November 7 - 8. A flare is observed simultaneously in X-ray and UV together with a quiescence. We find that during the flare event X-ray flux varies with UV with no significant time
Casares J.   +7 more
core   +2 more sources

Evaluation of a novel EHR sidecar application to display RA clinical outcomes during clinic visits: results of a stepped‐wedge cluster randomized pragmatic trial

open access: yesArthritis Care &Research, Accepted Article.
Objective We developed a novel EHR sidecar application to visualize key rheumatoid arthritis (RA) outcomes, including disease activity, physical function, and pain, via a patient‐facing graphical interface designed for use during outpatient visits (“RA PRO dashboard”).
Gabriela Schmajuk   +16 more
wiley   +1 more source

Leveraging immune checkpoint inhibitors in lung cancer patients with pre-existing autoimmune disease: clinical insights, optimal timing, and predictive biomarkers for optimal treatment outcomes

open access: yesFrontiers in Immunology
The use of immune checkpoint inhibitors (ICIs) has revolutionized cancer treatment, particularly in lung cancer. However, their use in patients with pre-existing autoimmune diseases (PADs) presents unique challenges.
Hui Yang   +5 more
doaj   +1 more source

Chromospheric condensations and magnetic field in a C3.6-class flare studied via He I D3 spectro-polarimetry

open access: yes, 2018
Context. Magnetic reconnection during flares takes place in the corona but a substantial part of flare energy is deposited in the chromosphere. However, high-resolution spectro-polarimetric chromospheric observations of flares are very rare.
Danilovic, Sanja   +4 more
core   +1 more source

COVID‐19 Vaccination is not Associated with the Development of Idiopathic Inflammatory Myositis in U.S. Veterans

open access: yesArthritis Care &Research, Accepted Article.
Objective Several case reports have proposed a potential association between COVID‐19 vaccination and the subsequent development of idiopathic inflammatory myositis (IIM). This study examined prior COVID‐19 vaccination in US Veterans who developed new‐onset IIM compared to those without new‐onset IIM.
Caleb Hernández   +10 more
wiley   +1 more source

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