Results 201 to 210 of about 136,458 (320)

Redox environment modulates aggregation of ataxin‐3 in vitro — Implications for drug screening of cysteine‐rich proteins

The FEBS Journal, EarlyView.
Redox environment modulates in vitro aggregation of Ataxin‐3, the protein implicated in spinocerebellar ataxia type 3. Reducing conditions stabilize native monomers and prevent aggregation, whereas oxidative conditions promote the formation of non‐native conformers and disulfide‐linked oligomers within the Josephin domain (JD).
Martyna Podlasiak, Martina Sollazzo, Elisa Monaca, Raffaele Sabbatella, Maria Agnese Morando, Oleg Chertkov, Laura Puglisi, Martina Mascellino, Anna Fricano, Sandra Macedo‐Ribeiro, Caterina Alfano   +10 more
wiley   +1 more source

Selective targeting of cortactin tandem repeat acetylation by human lysine deacetylases

The FEBS Journal, EarlyView.
Cortactin function is regulated by acetylation at several lysine residues within its tandem repeat region. Using genetic code expansion to generate cortactin variants containing precisely defined acetylation marks, we show that HDAC6 is the primary enzyme removing these modifications, with SIRT1 and SIRT2 also acting at selected sites but with lower ...
Jan Komarek, Miroslava Vosahlikova, Zsofia Kutil, Zora Novakova, Julia Kudlacova, Ruzena Tuckova, Marat Meleshin, Barbora Havlinova, Pavlina Jaklova, Jana Ptackova, Cordelia Schiene‐Fischer, Mike Schutkowski, Cyril Barinka   +12 more
wiley   +1 more source

Correlation Between Blood Glucose Indexes Generated by the Flash Glucose Monitoring System and Diabetic Vascular Complications. [PDF]

Diabetes Metab Syndr Obes, 2023
Sheng X, Li T, Hu Y, Xiong CS, Hu L.
europepmc   +1 more source

Persistent in vitro nociceptor hyperexcitability and axonal retraction produced by repeated paclitaxel doses

The FEBS Journal, EarlyView.
Repeated paclitaxel exposure causes long‐lasting nociceptor hyperexcitability and axonal retraction in adult sensory neurons. Using a long‐term primary nociceptor culture, we show that hyperexcitability is mediated by sequential upregulation of NaV1.8, TRPV1, TRPA1, and TRPM8 channels.
Angela Lamberti, Victor Moreno Lozano, Asia Fernández‐Carvajal, Antonio Ferrer‐Montiel   +3 more
wiley   +1 more source

Evaluation of low and high interstitial glucose concentrations in healthy, nondiabetic dogs using a flash glucose monitoring system. [PDF]

J Vet Intern Med
Brisman RF, Palma DA, Fox PR.
europepmc   +1 more source

Association between continuous glucose monitoring metrics and diabetic retinopathy and albuminuria among Japanese individuals with type 1 diabetes

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Aims/Introduction This study aimed to clarify the relationship between glucose metrics measured by continuous glucose monitoring (CGM) and diabetic retinopathy (DR) and albuminuria among Japanese individuals with type 1 diabetes mellitus. Materials and Methods The study included 294 individuals with type 1 diabetes (68.7% women) who underwent ...
Yuichiro Kondo, Ryo Kubota, Rika Suda, Yukiko Hasegawa, Junko Oya, Satoshi Takagi, Hiroko Takaike, Junnosuke Miura, Tomoko Nakagami   +8 more
wiley   +1 more source

Insulin Autoimmune Syndrome Associated With Hashimoto Thyroiditis and Nodular Thyroid Disease: Clinical Management With Flash Glucose Monitoring and Prednisolone Therapy. [PDF]

Am J Case Rep
Nowak A, Morawiec-Sławek K, Motyka M, Trofimiuk-Müldner M, Hubalewska-Dydejczyk A.   +4 more
europepmc   +1 more source

Hypoglycemia measured by flash glucose monitoring system predicts liver-related events in chronic liver disease patients. [PDF]

Sci Rep, 2023
Sasaki R, Taura N, Nakao Y, Fukushima M, Haraguchi M, Miuma S, Miyaaki H, Nakao K.   +7 more
europepmc   +1 more source

Acute freshwater CO2 exposure does not impair seawater transfer in three different sizes of Atlantic salmon (Salmo salar) subjected to different photoperiod manipulations

Journal of Fish Biology, EarlyView.
Abstract There is a growing interest in Atlantic salmon (Salmo salar) aquaculture to extend the time fish are reared in freshwater (FW) recirculating aquaculture systems (RAS), producing larger FW salmon that can then be induced to undergo smoltification before transfer into marine net pens for grow‐out and harvest.
Le Thi Hong Gam, Daniel W. Montgomery, Daniel S. Laronde, Rachael Mackinnon, Jeffrey G. Richards, Colin J. Brauner   +5 more
wiley   +1 more source

Accuracy of Flash Glucose Monitoring in Hemodialysis Patients With and Without Diabetes Mellitus. [PDF]

Exp Clin Endocrinol Diabetes, 2023
Weber MR, Diebold M, Wiesli P, Kistler AD.   +3 more
europepmc   +1 more source