Results 221 to 230 of about 32,934 (280)

Update on Non‐Biological and RNA‐Based Therapeutics in Chronic Inflammatory Diseases: Precision Medicine Through Small Molecules: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter, I. M. Adcock, C. Benito‐Villalvilla, R. Bianchini, L. Bjermer, G. Caramori, L. Cari, K. F. Chung, Z. Diamant, I. Eguiluz‐Gracia, E. F. Knol, M. Jesenak, F. Levi‐Schaffer, G. Nocentini, L. O'Mahony, O. Palomares, F. Redegeld, M. Sokolowska, B. Van Esch, M. Zurlo, C. Stellato   +20 more
wiley   +1 more source

Butyrophilin 2A2 promotes T cell immunoregulation via CD45 phosphatase activation and protects against murine autoimmune glomerulonephritis and pregnancy loss. [PDF]

Nat Commun
Ali S, Berg AH, Yamashita M, Covarrubias AE, Mundell J, Shah PN, Zhang R, Dupont V, Shin BH, Yang S, Katiki M, Murali R, Pisarska MD, Thadhani R, Heeger PS, Jordan SC, Karumanchi SA.   +16 more
europepmc   +1 more source

Structural Basis for Trivalent Cross‐Linking of a Patient‐Derived IgE Antibody by the Major Peanut Allergen Ara h 2.0201

Allergy, EarlyView.
Graphical The crystal structure of a major peanut allergen Ara h 2.0201 in a complex with a human‐derived IgE Fab fragment has been determined. The immunocomplex shows the trivalent binding of Fabs, creating a cross‐linked structure effective in the formation of large complexes on the surface of effector cells. Hydroxylation of proline has implications
Tarja Parkkinen, Heidi Heiniluoto, Janne Jänis, Kristiina Takkinen, Juha Rouvinen   +4 more
wiley   +1 more source

Fecal microbiota transplants (FMT) of three distinct human communities to germ-free mice exacerbated inflammation and decreased lung function in their offspring. [PDF]

mBio
Moya Uribe IA, Terauchi H, Bell JA, Zanetti A, Jantre S, Huebner M, Arshad SH, Ewart SL, Mansfield LS.   +8 more
europepmc   +1 more source

Expression reduction and a variant of a P450 gene mediate chlorpyrifos resistance in Tetranychus urticae Koch. [PDF]

J Adv Res
Xu D, Liao H, He C, Wang K, Dong R, Zhang Y, Guo Z, Yang X, Xie W, Crickmore N, Wang S.   +10 more
europepmc   +1 more source

α2-3 Sialic Acids-Decorated Allergens Exert a Tolerogenic Effect on CD4+ T Cells from Der p 2-Allergic Patients.

Int Arch Allergy Immunol
Keumatio Doungtsop BC, Nardini E, Peterse EE, Kalay H, Versteeg SA, van Ree R, de Jong EEC, van Kooyk Y.   +7 more
europepmc   +1 more source

Transkingdom mechanism of MAMP generation by chitotriosidase feeds oligomeric chitin from fungal pathogens and allergens into TLR2-mediated innate immune sensing. [PDF]

Front Immunol
Chang TH, Cardona Gloria Y, Hellmann MJ, Richardo T, Greve CL, Le Roy D, Roger T, Bork F, Bugl S, Jakob J, Sonnberger J, Kasper L, Hube B, Pusch S, Gow NAR, Sørlie M, Tøndervik A, Moerschbacher BM, Weber ANR.   +18 more
europepmc   +1 more source

CHEMICAL CONTROL OF THE RUST MITE PHYLLOCOPTRUTA OLEIVORA ASHMEAD, FLAT MITE BREVIPALPUS CALIFORNICUS BANKS AND ITS SIDE EFFECT ON AMBLYSEIUS SCUTALIS (ATHIAS-HENRIOT) ON CITRUS TREES.

Egyptian Journal of Agricultural Research, 1993
openaire   +1 more source

Discovery and demonstration of the temperature stress response functions of Dermatophagoides farinae proteins 1 and 2. [PDF]

BMC Genomics
Zhang W, Niu D, Zhao Y, Hu L, Guan C, Chai R.   +5 more
europepmc   +1 more source

Circulating Type 2 Memory B Cell Frequency Is a Biomarker for Allergen Immunotherapy Efficacy in Patients With Allergic Rhinitis

Allergy, EarlyView.
Yue Ma, Shuying Li, Lei Ye, Lin Qiu, Jiayu Wu, Jiaying Li, Xian Feng, Wei Qian, Xiangping Yang, Huabin Li, Hongfei Lou   +10 more
wiley   +1 more source