Results 91 to 100 of about 867,968 (343)

Germline TP53 Mutations Causing Diamond–Blackfan Anemia: A French Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Diamond–Blackfan anemia is a rare congenital erythroblastopenia typically caused by mutations in ribosomal protein genes. Recently, gain‐of‐function mutations in TP53 have been identified as a novel cause of Diamond–Blackfan anemia. We report two French patients who both harbored a heterozygous TP53 deletion (NM_000546.5: c.1077delA; p ...
Rafael Moisan, Lydie Da Costa, Ludivine David Nguyen, Heloise Chosseler, Audrey Riquet, Benedicte Bruno, Melissa Barbati   +6 more
wiley   +1 more source

Signatures and flatness.

Journal für die reine und angewandte Mathematik (Crelles Journal), 1993
Let \(Y\subset\mathbb{R}^ n\) be a codimension one analytic set, and fix a signature \(\sigma\) on \(\mathbb{R}^ n\backslash Y\) \((\sigma\) associates a \(\text{sign}+1\) or \(-1\) to each connected component of \(\mathbb{R}^ n\backslash Y)\). The signature \(\sigma\) is admissible at \(x\in Y\) when the germ \(\sigma_ x\) is induced by a germ of ...
ACQUISTAPACE, FRANCESCA, BROGLIA, FABRIZIO   +1 more
openaire   +3 more sources

Classifications, sedimentary features and facies associations of tidal flats

Journal of Palaeogeography, 2013
Significant progress has been achieved in the research of tide-dominated environments in the past two decades. These studies highlight both the importance and diversity of tidal flats in modern coastal environments.
Fan Daidu
doaj   +1 more source

On the development and evolution of wear flats in microcrystalline sintered alumina grinding wheels

, 2018
Wheel wear is a critical issue for grinding process optimization. This is why it receives so much attention both from Academia and industry. The development of new generations of abrasive wheels requires improving the understanding of the mechanisms ...
L. Godino, I. Pombo, J. A. Sánchez, J. Álvarez   +3 more
semanticscholar   +1 more source

Bacterial community structure and function shift along a successional series of tidal flats in the Yellow River Delta

Scientific Reports, 2016
Coastal ecosystems play significant ecological and economic roles but are threatened and facing decline. Microbes drive various biogeochemical processes in coastal ecosystems.
Xiaofei Lv, Bin Ma, Junbao Yu, Scott X. Chang, Jianming Xu, Yunzhao Li, Guangmei Wang, G. Han, Guan Bo, Xiaojing Chu   +9 more
semanticscholar   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source

The Static Failure of Adhesively Bonded Metal Laminate Structures: A Cohesive Zone Approach [PDF]

, 1987
Data on distribution, ecology, biomass, recruitment, growth, mortality and productivity of the West African bloody cockle Anadara senilis were collected at the Banc d'Aguuin, Mauritania, in early 1985 and 1986.
K. B. Katnam, A. D. Crocombe, H. Khoramishad, I. A. Ashcroft, Higgins A., Dattaguru B., Reddy J. N., Crocombe A. D., Hildebrand M., Tvergaard V., Tvergaard V., Rahul Kumar P., Goncalves J. P. M., Blackman B. R. K., Ferracin T., Crocombe A. D., Liljedahl C. D. M., Feraren P., Kafkalidis M. S., Barrenblatt G. I., Dugdale D. S., Hillerborg A., Alfano G., Diehl T., Diehl T., Alfano G., Liljedahl C. D. M., Liljedahl C. D. M., Naghdali C., Benzeggagh M. L.   +29 more
core   +3 more sources

Flat connections from flat gerbes [PDF]

Fortschritte der Physik, 2002
We discuss some aspects of heterotic-Type I duality. We focus on toroidal compactification, with special attention for the topology of the gauge group, and the topology of the bundle. We review the arguments leading to a classification of Spin(32)/Z_2-bundles over tori, suitable for string compactifications.
openaire   +3 more sources

Land claim and loss of tidal flats in the Yangtze Estuary

Scientific Reports, 2016
Tidal flats play a critical role in supporting biodiversity and in providing ecosystem services but are rapidly disappearing because of human activities.
Ying Chen, Jinwei Dong, Xiangming Xiao, Min Zhang, Bo Tian, Yunxuan Zhou, Bo Li, Z. Ma   +7 more
semanticscholar   +1 more source

‘They Need to Hear You Say It’: Healthcare Professionals’ Perspectives on Barriers and Enablers to End‐of‐Life Discussions With Adolescents and Young Adults With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee, Holly Evans, Claire E. Wakefield, Antoinette Anazodo, Richard J. Cohn, Brittany C. McGill, Elizabeth A. Lobb, Lori Wiener, Madeleine L. Juhrmann, Ursula M. Sansom‐Daly   +9 more
wiley   +1 more source