Gene- and pathway-level analyses of iCOGS variants highlight novel signaling pathways underlying familial breast cancer susceptibility. [PDF]
Abstract Single‐nucleotide polymorphisms (SNPs) in over 180 loci have been associated with breast cancer (BC) through genome‐wide association studies involving mostly unselected population‐based case‐control series. Some of them modify BC risk of women carrying a BRCA1 or BRCA2 (BRCA1/2) mutation and may also explain BC risk variability in BC‐prone ...
Lonjou C +47 more
europepmc +2 more sources
Un enterrement à Paris de Gustave Flaubert (L’Éducation sentimentale, 1869)
“A Burial at Paris” by Gustave Flaubert (Sentimental Education, 1869) The paper focuses on the passage on the burial of the banker Dambreuse in chapter IV of the third part of Sentimental Education (
Agnieszka Kocik
doaj +2 more sources
Familial breast cancer and DNA repair genes: Insights into known and novel susceptibility genes from the GENESIS study, and implications for multigene panel testing. [PDF]
Pathogenic variants in BRCA1 and BRCA2 only explain the underlying genetic cause of about 10% of hereditary breast and ovarian cancer families. Because of cost‐effectiveness, multigene panel testing is often performed even if the clinical utility of testing most of the genes remains questionable.
Girard E +63 more
europepmc +2 more sources
« Madame Bovary, par M. Gustave Flaubert »
Alfred-Auguste Cuvillier-Fleury
doaj +2 more sources
Low life: William Hogarth, visual culture and sociologies of art
Abstract This paper is an effort to understand Hogarth's unique position in early eighteenth century London, so as to grasp the rich complexity of his work. It begins by tracing two rival competing positions in the sociology of art, derived from Becker and Bourdieu, before taking a closer look at how Hogarth's work conjures up a new vision of the world,
Eamonn Carrabine
wiley +1 more source
O objetivo do presente artigo é perscrutar a tese sartreana da constituição passiva do escritor francês pós-romântico Gustave Flaubert através de algumas passagens da primeira parte “La Constitution”, do primeiro tomo da última grande obra de Sartre, L ...
Gustavo Fujiwara
semanticscholar +1 more source
Effi Briest and the work on genre
Abstract Ever since Erich Auerbach’s harsh verdict in Mimesis, the German realist novel has been seen as a peripheral phenomenon in the history of nineteenth‐century literature. Criticized for being too idealizing, insular, or simply irrelevant, it has gone down in literary history as a less modern form of realism, not being able to join the realist ...
Fredrik Wilhelm Renard
wiley +1 more source
Knowledge in George Eliot's Middlemarch and Gustave Flaubert's Bouvard et Pécuchet
:This article considers late-nineteenth-century questioning of the progressive power of accumulated knowledge by examining two novels: Gustave Flaubert's final, incomplete novel, Bouvard et Pécuchet (1881), and George Eliot's Middlemarch (1871–72).
Lucy O’Meara
semanticscholar +1 more source
Desire, Death and Sexual Politics in Gustave Flaubert’s Madame Bovary
This paper examines the interface of desire, sexual politics and death through a literary-critical study of Gustave Flaubert’s Madame Bovary. The study focuses on the characterization of Emma which allows for a more in-depth and thorough exploration of ...
Aminu Ahmed Nuru
semanticscholar +1 more source
EXPLORING EMMA BOVARY’S DIFFUSED PERSONALITY IN GUSTAVE FLAUBERT’S MADAME BOVARY NOVEL
This study aimed to explore Emma’s diffused personality in the novel Madame Bovary by Gustave Flaubert. This study used a qualitative approach. The data collection technique used documentation.
Z. Tlonaen
semanticscholar +1 more source

