Results 131 to 140 of about 68,853 (304)

The interferon-stimulated gene IFITM3 restricts West Nile virus infection and pathogenesis [PDF]

, 2016
The interferon-induced transmembrane protein (IFITM) family of proteins inhibit infection of several different enveloped viruses in cell culture by virtue of their ability to restrict entry and fusion from late endosomes.
Bradbury LE, Chen YX, Ebel GD, Evans SS, Frey M, Omalu BI, Takahashi S   +6 more
core   +2 more sources

Membrane and envelope virus proteins co-expressed as lysosome associated membrane protein (LAMP) fused antigens: a potential tool to develop DNA vaccines against flaviviruses

Anais da Academia Brasileira de Ciências, 2009
Vaccination is the most practical and cost-effective strategy to prevent the majority of the flavivirus infection to which there is an available vaccine. However, vaccines based on attenuated virus can potentially promote collateral side effects and even
Rafael Dhalia, Milton Maciel Jr., Fábia S.P. Cruz, Isabelle F.T. Viana, Mariana L. Palma, Thomas August, Ernesto T.A. Marques Jr.   +6 more
doaj   +1 more source

Crystal structure of the NS3-like helicase from Alongshan virus

IUCrJ, 2020
Alongshan virus (ALSV) is an emerging human pathogen that was identified in China and rapidly spread to the European continent in 2019, raising concerns about public health.
Xiaopan Gao, Kaixiang Zhu, Justyna Aleksandra Wojdyla, Pu Chen, Bo Qin, Ziheng Li, Meitian Wang, Sheng Cui   +7 more
doaj   +1 more source

Structural basis for STAT2 suppression by flavivirus NS5

Nature Structural & Molecular Biology, 2020
Suppressing cellular signal transducers of transcription 2 (STAT2) is a common strategy that viruses use to establish infections, yet the detailed mechanism remains elusive, owing to a lack of structural information about the viral–cellular complex ...
Boxiao Wang, Stephanie Thurmond, K. Zhou, M. T. Sánchez-Aparicio, Jian Fang, Jiuwei Lu, Linfeng Gao, Wendan Ren, Yanxiang Cui, Ethan C. Veit, HeaJin Hong, M. Evans, S. O’Leary, A. García-Sastre, Z. Zhou, R. Hai, Jikui Song   +16 more
semanticscholar   +1 more source

Tick‐Borne Encephalitis (TBE) Vaccine in the National Immunisation Programme—For Whom, When and Where?

Acta Paediatrica, EarlyView.
ABSTRACT The incidence of Tick‐borne encephalitis (TBE) cases has increased. The presumed location of transmission of Tick‐borne encephalitis virus (TBEV) has been expanding increasingly in the western parts of Europe during the past decade. There has also been an increased incidence of surveillance‐reported TBE cases in southern Sweden and southern ...
H. H. Askling, D. Zavadska
wiley   +1 more source

Dengue and Zika virus cross-reactive human monoclonal antibodies protect against Spondweni virus infection and pathogenesis in mice [PDF]

, 2019
Summary: Spondweni virus (SPOV) is the flavivirus that is most closely related to Zika virus (ZIKV). Although SPOV causes sporadic human infections in Africa, recently it was found in Culex mosquitoes in Haiti.
Aliota, Ansarah-Sobrinho, Barba-Spaeth, Cerbino-Neto, Cugola, Culshaw, Dejnirattisai, Dejnirattisai, Dowd, Draper, Driggers, Elong Ngono, Falk, Fernandez, Fox, Goncé, Gorman, Govero, Grant, Haddow, Haddow, Halstead, Hasan, Hessell, Jagger, Kokernot, Lanciotti, Lazear, Ma, MacNamara, Mansuy, Mansuy, Mansuy, McDonald, Miner, Morrison, Morrison, Mukherjee, Nguyen, Oliphant, Pal, Pierson, Pierson, Platt, Richner, Rossi, Rouvinski, Sapparapu, Sheehan, Suy, Taraphdar, White, Zhao   +52 more
core   +3 more sources

The glycosylation deficiency of flavivirus NS1 attenuates virus replication through interfering with the formation of viral replication compartments

Journal of Biomedical Science
Background Flavivirus is a challenge all over the world. The replication of flavivirus takes place within membranous replication compartments (RCs) derived from endoplasmic reticulum (ER).
Shuhan Huang, Pan-Deng Shi, Xiao-Xuan Fan, Yang Yang, Cheng-Feng Qin, Hui Zhao, Lei Shi, Yali Ci   +7 more
doaj   +1 more source

Renaming of the genus Flavivirus to Orthoflavivirus and extension of binomial species names within the family Flaviviridae

Archives of Virology, 2023
T. Postler, M. Beer, B. Blitvich, J. Bukh, X. D. de Lamballerie, J. Drexler, A. Imrie, A. Kapoor, G. Karganova, P. Lemey, V. Lohmann, P. Simmonds, Donald B. Smith, J. Stapleton, J. Kuhn   +14 more
semanticscholar   +1 more source

Ubiquitination dynamics in human tumour viruses: Viral infection, oncogenesis and antiviral therapy

The FEBS Journal, EarlyView.
The ubiquitin system is essential for cellular homeostasis and regulates many processes. Viruses, including oncogenic ones, exploit or evade this system to survive and replicate. This review explores how human tumour viruses manipulate the ubiquitination system to complete their life cycle, evade immunity and promote cancer.
Oscar Trejo‐Cerro, Martina Bergant Marušič, Justyna Broniarczyk   +2 more
wiley   +1 more source

Prevalence of Flavivirus and Alphavirus in bats captured in the state of Yucatan, southeastern Mexico

One Health
Summary: Flavivirus (family Flaviviridae) and Alphavirus (family Togaviridae) are mosquito-borne viruses that poses a significant risk to public health worldwide.
Aaron Yeh-Gorocica, Marco Torres-Castro, Claudia Carrillo-Chan, Alejandro Suarez-Galaz, Melissa Suarez-Galaz, Wilson Moguel-Chin, Alonso Panti-May, Cesar Lugo-Caballero, Henry Puerta-Guardo, Juan Chable-Santos, Pablo Manrique-Saide, Guadalupe Ayora-Talavera, Celia Selem-Salas, Mario Frias-Casas, Antonio Rivero-Juarez   +14 more
doaj   +1 more source