Mechanism and structural diversity of exoribonuclease-resistant RNA structures in flaviviral RNAs
Subgenomic flavivirus RNAs are generated by a host exoribonuclease and play an important role in virus replication and pathogenesis. Here, the authors show the mechanism by which subgenomic flavivirus RNAs are generated and identify two structurally ...
Andrea MacFadden+8 more
doaj +1 more source
Establishment and Characterization of Japanese Encephalitis Virus-Specific, Human CD4 + T-Cell Clones: Flavivirus Cross-Reactivity, Protein Recognition, and Cytotoxic Activity [PDF]
Hirokuni Aihara+4 more
openalex +1 more source
Advances in Alphavirus and Flavivirus Research
Newly emerging viruses, primarily zoonotic or vector-borne, pose a persistent threat to public health and have led to outbreaks of global concern [...]
Young Chan Kim, Arturo Reyes-Sandoval
openaire +3 more sources
cis - and trans -Acting Elements in Flavivirus RNA Replication [PDF]
Alexander A. Khromykh+2 more
openalex +1 more source
Understanding flavivirus immunity is critical for the development of pan-flavivirus vaccines. Dendritic cells (DC) coordinate antiviral innate and adaptive immune responses, and they can be targeted by flaviviruses as a mechanism of immune evasion. Using
Ying-Ting Wang+15 more
doaj +1 more source
Substitutions at the Putative Receptor-Binding Site of an Encephalitic Flavivirus Alter Virulence and Host Cell Tropism and Reveal a Role for Glycosaminoglycans in Entry [PDF]
Eva Lee, Mario Lobigs
openalex +1 more source
Clinical perspectives of emerging pathogens in bleeding disorders. [PDF]
As a result of immunological and nucleic-acid screening of plasma donations for transfusion-transmissible viruses, and the incorporation of viral reduction processes during plasma fractionation, coagulation-factor concentrates (CFC) are now judged safe ...
Bozzette, Samuel+11 more
core +1 more source
Summary: Flavivirus (family Flaviviridae) and Alphavirus (family Togaviridae) are mosquito-borne viruses that poses a significant risk to public health worldwide.
Aaron Yeh-Gorocica+14 more
doaj
Deconvolution of pro- and antiviral genomic responses in Zika virus-infected and bystander macrophages. [PDF]
Genome-wide investigations of host-pathogen interactions are often limited by analyses of mixed populations of infected and uninfected cells, which lower sensitivity and accuracy.
Benner, Christopher+9 more
core