Results 281 to 290 of about 68,853 (304)

A broadly protective antibody that targets the flavivirus NS1 protein

Science, 2021
Two antibodies against flaviviruses Flaviviruses are a group of RNA viruses that include the human pathogens dengue virus, Zika virus, and West Nile virus.
Naphak Modhiran, Hao Song, Lidong Liu, Cheryl Bletchly, L. Brillault, Alberto A. Amarilla, Xiaoying Xu, J. Qi, Y. Chai, Stacey T M Cheung, Renee J. Traves, Y. X. Setoh, Summa Bibby, Connor A. P. Scott, Morgan E. Freney, N. Newton, A. Khromykh, Keith J. Chappell, David A. Muller, K. Stacey, M. Landsberg, Yi Shi, G. Gao, P. Young, D. Watterson   +24 more
semanticscholar   +1 more source

Flavivirus Entry Inhibitors

2022
Flaviviruses, including Dengue virus, Zika virus, Yellow fever virus, Japanese encephalitis virus, West Nile virus, cause thousands of deaths and millions of illnesses each year. The large outbreak of ZIKV in 2016 reminds us that flaviviruses can pose a serious threat to human safety and public health as emerging and re-emerging viruses. However, there
Yufeng, Yu, Lulu, Si, Yu, Meng
openaire   +2 more sources

Flavivirus Entry Inhibitors

ACS Infectious Diseases, 2015
Many flaviviruses are significant human pathogens that are transmitted by mosquitoes and ticks. Although effective vaccines are available for yellow fever virus, Japanese encephalitic virus, and tick-borne encephalitis virus, these and other flaviviruses still cause thousands of human deaths and millions of illnesses each year.
Qing Yin Wang, Pei Yong Shi
openaire   +3 more sources

A naturally isolated symbiotic bacterium suppresses flavivirus transmission by Aedes mosquitoes

Science
The commensal microbiota of the mosquito gut plays a complex role in determining the vector competence for arboviruses. In this study, we identified a bacterium from the gut of field Aedes albopictus mosquitoes named Rosenbergiella sp.
Liming Zhang, Daxi Wang, Peibo Shi, Juzhen Li, Jichen Niu, Jielong Chen, Gang Wang, Linjuan Wu, Lu Chen, Z. Yang, Susheng Li, J. Meng, Fangchao Ruan, Yuwen He, Hailong Zhao, Zirui Ren, Yibaina Wang, Yang Liu, Xiaolu Shi, Yunfu Wang, Qiyong Liu, Junhua Li, Penghua Wang, Jinglin Wang, Yibin Zhu, G. Cheng   +25 more
semanticscholar   +1 more source

Immunopathology of flavivirus infections

Immunology & Cell Biology, 2006
With the recent emergence of the flavivirus, West Nile virus (WNV), in particular, the New York strain of Lineage I WNV in North America in 1999, there has been a significant increase in activity in neurotropic flavivirus research. These viruses cause encephalitis that can result in permanent neurological sequelae or death. Attempts to develop vaccines
Meghann Teague Getts, Bimmi Shrestha, Sabita Rana, Nicholas J. C. King, Alison M. Kesson, Daniel R. Getts   +5 more
openaire   +3 more sources

Flavivirus vaccines

Vaccine, 1988
Diseases caused by flavivirus infection have been a scourge of mankind for over three centuries; with yellow fever, dengue fever and Russian spring-summer encephalitis causing epidemics resulting in thousands of fatalities. Due to the development of a safe and efficacious live-attenuated vaccine against yellow fever, this disease is no longer such a ...
openaire   +2 more sources

Flaviviruses and flavivirus vaccines

Vaccine, 2012
Several human-pathogenic flaviviruses (including yellow fever, dengue, Japanese encephalitis, West Nile and tick-borne encephalitis viruses) have a significant public health impact in different parts of the world and the potential of emerging in previously non-endemic regions.
Franz X. Heinz, Karin Stiasny
openaire   +3 more sources

Platelets in the pathogenesis of flavivirus disease

Current Opinion in Virology, 2022
Research on the role of platelets in modulating innate and adaptive host immune responses has gaining importance in the last two decades. Since the virus can directly interact with platelet receptors and modulate the host immune response, understanding the role of platelets in viral pathogenesis would pave way for novel therapeutic means.
Agiesh Kumar Balakrishna Pillai, Justin Jang Hann Chu, Vignesh Mariappan, Aashika Raagavi JeanPierre   +3 more
openaire   +2 more sources

Microscopy techniques in flavivirus research

Micron, 2014
The Flavivirus genus is composed of many medically important viruses that cause high morbidity and mortality, which include Dengue and West Nile viruses. Various molecular and biochemical techniques have been developed in the endeavour to study flaviviruses.
Mun Keat Chong, Anthony Jin Shun Chua, Terence Tze Tong Tan, Suat Hoon Tan, Mah Lee Ng   +4 more
openaire   +3 more sources

Recombination and flavivirus vaccines: a commentary

Vaccine, 2005
A review article recently appeared in the Lancet by Seligman and Gould, in which the authors raise a safety concern for flavivirus vaccines based on possible recombination between wild-type viruses and live, attenuated vaccine viruses. Flaviviruses are small enveloped viruses with a single positive sense RNA genome containing a single long open reading
Monath, Thomas P., Kanesa-thasan, Niranjan, Guirakhoo, Farshad, Pugachev, Konstantin, Almond, Jeffrey, Lang, Jean, Quentin-Millet, Marie-Jose, Barrett, Alan D. T., Brinton, Margo A., Cetron, Martin S., Barwick, Rachel S., Chambers, Thomas J., Halstead, Scott B., Roehrig, John T., Kinney, Richard M., Rico-Hesse, Rebecca, Strauss, James H.   +16 more
openaire   +4 more sources