Results 21 to 30 of about 52,238 (309)

Anticancer Flavonoids Are Mouse-Selective STING Agonists [PDF]

open access: yesACS Chemical Biology, 2013
The flavonoids FAA and DMXAA showed impressive activity against solid tumors in mice but failed clinical trials. They act on a previously unknown molecular target(s) to trigger cytokine release from leukocytes, which causes tumor-specific vascular damage and other antitumor effects.
Sujeong, Kim   +5 more
openaire   +2 more sources

In Vitro and in vivo anti-tumoral effects of the flavonoid apigenin in malignant mesothelioma [PDF]

open access: yes, 2017
Malignant mesothelioma (MM) is a tumor arising from mesothelium. MM patients' survival is poor. The polyphenol 4',5,7,-trihydroxyflavone Apigenin (API) is a "multifunctional drug". Several studies have demonstrated API anti-tumoral effects.
Andrea Modesti   +13 more
core   +2 more sources

Screening the effect of four ultrasound-assisted extraction parameters on hesperidin and phenolic acid content of aqueous citrus pomace extracts [PDF]

open access: yes, 2018
Polyphenols of citrus by-products, due to their antioxidant and antimicrobial activities, could be valorized by pharmaceutical and food industries, adding a value to the citrus processing companies.
Bowyer, Michael C.   +6 more
core   +2 more sources

In-vitro antioxidant and anti-inflamatory activities of Pituranthos chloranthus and Artemisia vulgaris from Tunisia [PDF]

open access: yes, 2020
Pituranthos chloranthus and Artemisia vulgaris L. are two of the most important aromatic and medicinal species from the Apiaceae and Asteraceae families, respectively. They are traditionally used in certain pathologies in which inflammatory processes are
AAZZA, Smail   +3 more
core   +1 more source

Transcriptomic and Non-Targeted Metabolomic Analyses Reveal the Flavonoid Biosynthesis Pathway in Auricularia cornea

open access: yesMolecules, 2022
Flavonoids, which are abundant in plants, are recognized for their antioxidant and anticancer roles in clinical applications. However, little is known about the molecular basis of flavonoid biosynthesis in fungi. In this study, we found that inclusion of
Li Meng   +7 more
doaj   +1 more source

Phytoestrogens [PDF]

open access: yes, 2004
Collectively, plants contain several different families of natural products among which are compounds with weak estrogenic or antiestrogenic activity toward mammals.
Adlercreutz H   +37 more
core   +1 more source

In Vitro Antioxidant and Anticancer Activity of Flavonoid Fraction from the Aerial Parts of Cissus quadrangularis Linn. against Human Breast Carcinoma Cell Lines

open access: yesJournal of Chemistry, 2013
Aim. The present study aimed to isolate flavonoid fraction from the aerial parts of Cissus quadrangularis and to evaluate its antioxidant and anticancer potential using in vitro assay system. Methods. Total phenolic and flavonoid contents were calculated
A. Vijayalakshmi   +3 more
doaj   +1 more source

Synergistic effects of flavonoids and paclitaxel in cancer treatment: a systematic review

open access: yesCancer Cell International, 2023
Paclitaxel is a natural anticancer compound with minimal toxicity, the capacity to stabilize microtubules, and high efficiency that has remained the standard of treatment alongside platinum-based therapy as a remedy for a variety of different ...
Solmaz Asnaashari   +2 more
doaj   +1 more source

Pretreatment of citrus by-products affects polyphenol recovery:a review [PDF]

open access: yes, 2018
A large amount of citrus waste is generated annually. This waste is of great economic worth, since it contains high levels of polyphenols, which have attracted scientific interest due to their potent antimicrobial and antiradical activities. Pretreatment
Bowyer, Michael C.   +7 more
core   +2 more sources

Flavonoids: A versatile source of anticancer drugs

open access: yesPharmacognosy Reviews, 2011
An exponential increase in the number of studies investigating how different components of the diet interact at the molecular and cellular level to determine the fate of a cell has been witnessed. In search for anticancer drugs compelling data from laboratories, epidemiologic investigations, and human clinical trials showed that flavonoids have ...
Chahar, Maheep K.   +3 more
openaire   +3 more sources

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