SAR, QSAR and Docking of Anticancer Flavonoids and Variants: A Review [PDF]
Flavonoids are phenolic compounds, secondary metabolites of plants that cause several benefits to our health, including helping the treatment against cancer. These pharmacological properties are associated with the ability of flavonoids in attenuating the generation of reactive oxygen species, acting as chelate compounds or affecting the oxi-redox ...
Luciana, Scotti +5 more
openaire +2 more sources
Machine Learning Accelerates Crystallization for Structure Determination
Single‐crystal X‐ray diffraction (SCXRD) is often constrained by the difficulty of obtaining suitable crystals. Here, a machine learning‐accelerated co‐crystal discovery workflow is established for a crystalline mate strategy that achieves over 95% prediction accuracy and experimentally delivers 114 co‐crystals from 120 candidates.
Cui‐Zhou Luan +10 more
wiley +2 more sources
Vitex agnus-castus L. د ا رسة الفعالية البايولوجية لبعض مستخلصات أو ا رق نبات كف مريم
In this study, the antibacterial activity of some Leaves Extracts of (Vitex agnus-castus L.)were determinated against two species of bacteria Escherichia coli and Staphylococcus aurous, These extracts including hot ethanolic 70% extract , hot methanolic ...
علي عبود شريف +2 more
doaj +2 more sources
Antiglycation activity and HT-29 cellular uptake of aloe-emodin, aloin, and aloe arborescens leaf extracts [PDF]
Aloe arborescens is a relevant species largely used in traditional medicine of several countries. In particular, the decoction of leaves is prepared for various medicinal purposes including antidiabetic care. The aim of this research was the study of the
Baronchelli, F. +3 more
core +1 more source
Prunin: An Emerging Anticancer Flavonoid
Despite the substantial advances in cancer therapies, developing safe and effective treatment methodologies is critical. Natural (plant-derived compounds), such as flavonoids, might be crucial in developing a safe treatment methodology without toxicity toward healthy tissues.
Juie Nahushkumar Rana, Sohail Mumtaz
openaire +2 more sources
Involvement of the leaf-specific multidrug and toxic compound extrusion (MATE) transporter Nt-JAT2 in vacuolar sequestration of nicotine in Nicotiana tabacum [PDF]
Alkaloids play a key role in higher plant defense against pathogens and herbivores. Following its biosynthesis in root tissues, nicotine, the major alkaloid of Nicotiana species, is translocated via xylem transport toward the accumulation sites, leaf ...
Goossens, Alain +11 more
core +8 more sources
Redox control of multidrug resistance and Its possible modulation by antioxidants [PDF]
Clinical efficacy of anticancer chemotherapies is dramatically hampered by multidrug resistance (MDR) dependent on inherited traits, acquired defence against toxins, and adaptive mechanisms mounting in tumours.
Cort, A. +4 more
core +3 more sources
A REVIEW OF THE ANTICANCER NATURAL PRODUCTS: ALKALOIDS, FLAVONOIDS
According to the international agency for research on cancer 1 in 5 people develop cancer during their lifetime, suggesting that more than 50 million people are living within five years of a past cancer diagnosis (World Health Organization (WHO, 2020, para. 1).
Ghazaee Parchami +1 more
openaire +1 more source
Mushrooms produce a large number of medicinal bioactive metabolites with antioxidant, anticancer, antiaging, and other biological activities. However, whether they produce flavonoids and, if so, how they synthesize them remains a matter of some debate ...
Shixin Wang +4 more
doaj +1 more source
Immunomodulator Activity Of An Isolate From Artocarpus Champeden Spreng. On Cytotoxicity Function Of Cd8+ Of Mice [PDF]
Research of traditional medicine is important to maximize the utilization of natural resources. Artocarpus champeden Spreng. is one of medicinal plants that must be studied because a lot of diseases have been treated traditionally with this plant, such ...
Kartini, Kartini
core

