Epidemiological and molecular characterisation of flea infestations in dogs and cats in mainland Portugal [PDF]
Background Fleas are major ectoparasites of dogs and cats, with significant veterinary and public health implications. This study aimed to estimate the prevalence of flea infestation in dogs and cats in mainland Portugal, identify associated risk factors
Carla Maia, André Pereira
exaly +5 more sources
A reverse vaccinology approach to the identification and characterization of Ctenocephalides felis candidate protective antigens for the control of cat flea infestations. [PDF]
Background Despite the abundance of the domestic cat flea, Ctenocephalides felis (Bouché, 1835) and disease risks associated with them, flea control is difficult and requires the development of new control interventions such as vaccines. In this study, a
Contreras M +5 more
europepmc +3 more sources
Background A novel chewable oral tablet containing sarolaner, moxidectin and pyrantel (Simparica Trio™) has recently been developed to provide persistent protection against flea and tick infections for a month, treatment of hookworm and roundworm ...
Csilla Becskei, Sean P Mahabir
exaly +4 more sources
Efficacy and safety of sarolaner (Simparica®) in the treatment and control of naturally occurring flea infestations in dogs presented as veterinary patients in Australia. [PDF]
Background The efficacy and safety of a novel isoxazoline compound, sarolaner (Simparica®, Zoetis) and spinosad (Comfortis®, Elanco) as a positive control were evaluated for the treatment and control of natural flea infestations on dogs in two randomised,
Packianathan R +5 more
europepmc +3 more sources
Impact of habitat modifications on flea (Siphonaptera) infestation dynamics of non-volant small mammals across wildlife-human interfaces in Tanzania. [PDF]
Changes in natural habitats affect the population density of small mammals, which in turn influences ectoparasite populations. This study explores how human-induced habitat modifications impact flea infestations of non-volant small mammals considering ...
Msoffe VT +6 more
europepmc +3 more sources
Laboratory studies evaluating the efficacy of a novel orally administered combination product containing sarolaner, moxidectin and pyrantel (Simparica Trio™) for the treatment and control of flea infestations on dogs. [PDF]
Background Five studies were conducted to evaluate a novel oral combination tablet containing sarolaner, moxidectin and pyrantel (Simparica Trio™), for efficacy against induced flea infestations, speed of kill and effects on flea reproduction on dogs ...
Kryda K +9 more
europepmc +2 more sources
Safety and efficacy of a new spot-on formulation of selamectin plus sarolaner in the treatment and control of naturally occurring flea infestations in cats presented as veterinary patients in Australia. [PDF]
Background The safety and efficacy of a new spot-on formulation of selamectin plus sarolaner were evaluated for the treatment and control of natural flea infestations on cats in two non-randomised, multi-centre clinical trials conducted in 8 different ...
Packianathan R +4 more
europepmc +2 more sources
Safety and efficacy of a novel oral chewable combination tablet containing sarolaner, moxidectin and pyrantel (Simparica Trio™) against natural flea infestations in client-owned dogs in the USA. [PDF]
Background One randomized, controlled clinical field study was conducted in 18 general veterinary practices throughout the USA to evaluate the safety and efficacy of a novel oral chewable combination tablet, Simparica Trio™, containing sarolaner ...
Kryda K, Mahabir SP, Inskeep T, Rugg J.
europepmc +2 more sources
Molecular detection of <i>Mycoplasma</i> <i>haemofelis</i> in cats infested with <i>Ctenocephalides felis</i> in Padang, West Sumatra, Indonesia. [PDF]
Background: Mycoplasma haemofelis infection is considered an important feline disease and is suspected to be transmitted via the ectoparasitic vector Ctenocephalides felis, particularly in tropical areas. Aim: This study aimed to detect M.
Rahayu H +4 more
europepmc +2 more sources
Assessment of lotilaner (Credelio® CAT) for control of in-home Ctenocephalides felis infestations. [PDF]
Background Flea infestations remain a major issue in veterinary medicine. Highly effective flea control for dogs and cats remains the foundation for eliminating infestations from homes and improving skin conditions associated with flea-feeding.
Sutherland C +12 more
europepmc +2 more sources

