Results 141 to 150 of about 33,295 (296)
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Artificial Intelligence in transfusion medicine: a paradigm shift on the horizon. [PDF]
Cognasse F +3 more
europepmc +1 more source
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura +19 more
wiley +1 more source
Breeding Chlorophyll-Deficient Mutants of <i>Chlorella vulgaris</i> to Enhance Consumer Acceptance. [PDF]
Olsen ML +11 more
europepmc +1 more source
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara +3 more
wiley +1 more source
Mapping Socioecological Interconnections in One Health Across Human, Animal, and Environmental Health: A Scoping Review Protocol. [PDF]
Medeiros JFD +13 more
europepmc +1 more source

