Results 141 to 150 of about 49,950 (284)

Indicators to identify cancer screening providers with suboptimal case detection: A scoping review

open access: yesInternational Journal of Cancer, Volume 158, Issue 9, Page 2339-2358, 1 May 2026.
What's new? Quality control of cancer screening programs is essential to maintaining high public health standards. Here, the authors reviewed monitoring of case detection in cervical and colorectal cancer screening programs in Europe, and evaluated its effectiveness. They analysed 20 different measures used for this purpose and showed that many of them
Jiayao Lei   +5 more
wiley   +1 more source

No Dye Fits All: Illuminating the Challenges of Fluorescent Extracellular Vesicle Labeling

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 5, May 2026.
ABSTRACT The widespread use of fluorescent dyes for extracellular vesicle (EV) labeling has substantially improved our ability to trace EVs in vitro, ex vivo, and in vivo. However, interpretability of these experiments remains limited by methodological challenges, including incomplete dye removal, dye‐associated artifacts, and intrinsic EV ...
Petra Vrdoljak   +9 more
wiley   +1 more source

Clinical Outcome Assessments in Parkinson's Disease: A Scoping Review of Current Rating Scales and Future Needs

open access: yesMovement Disorders Clinical Practice, Volume 13, Issue 5, Page 1124-1146, May 2026.
Abstract Background Clinical outcome assessments (COAs) are essential for evaluating symptom severity, treatment response, and disease progression in Parkinson's disease (PD). As clinical knowledge evolves, it is necessary to revisit the recommendation status on the COAs to ensure their continued relevance and validity. Objectives To provide an updated
Evita Papathoma   +14 more
wiley   +1 more source

Deforming the Double‐Scaled SYK and Reaching the Stretched Horizon From Finite Cutoff Holography

open access: yesFortschritte der Physik, Volume 74, Issue 5, May 2026.
ABSTRACT We study the properties of the double‐scaled SYK (DSSYK) model under chord Hamiltonian deformations based on finite cutoff holography for general dilaton gravity theories with Dirichlet boundaries. The formalism immediately incorporates a lower‐dimensional analog of TT¯(+Λ2)$\text{T}\overline{\text{T}}(+\Lambda _2)$ deformations, denoted T2 ...
Sergio E. Aguilar‐Gutierrez
wiley   +1 more source

Mechanistic Insights Into Nitric Oxide Capture and Release in a Radical‐Scavenging Zinc Ascorbate Metal–Organic Framework

open access: yesSmall Science, Volume 6, Issue 5, May 2026.
A zinc–ascorbate MOF (bioNICS‐1) enables tuneable nitric oxide (NO) capture and humidity‐triggered release through defect engineering and structural modulation. Organic acid treatment enhances binding site accessibility and retention strength.
Tia Kristian Tajnšek   +13 more
wiley   +1 more source

Telomere Dysfunction and Proteostasis Decline Define Distinct Pathways of Cellular Senescence in the Human Respiratory Tract

open access: yesAging Cell, Volume 25, Issue 5, May 2026.
Telomere shortening occurs with age in the respiratory epithelium, but telomere dysfunction‐induced foci (TIF) accumulate only late in life. In contrast, proteostasis decline emerges earlier and correlates with functional impairment, suggesting it may be a primary driver of cellular senescence during physiological aging.
Céline Coquette   +20 more
wiley   +1 more source

Feedback control of excitability and high K+ induced epileptiform bursts in male rat hippocampal slices with a photocaged adenosine A1 receptor agonist

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 10, Page 2578-2591, May 2026.
Background and Purpose Adenosine is a potent regulator of neurotransmission and neuronal excitability, through activation of Gi coupled adenosine A1 receptors (A1Rs). Adenosine has gained interest as an anticonvulsant because of its endogenous involvement in ending seizure activity, but peripheral side effects require local application.
Erine Craey   +8 more
wiley   +1 more source

Adapted Physical Activity for Elderly People and National Policies. A Comparative Investigation

open access: yesSocial Policy &Administration, Volume 60, Issue 3, Page 441-449, May 2026.
ABSTRACT The global demographic transition presents challenges and opportunities for Western societies, affecting biological, psychological, and social aspects. Ageing is linked to a decline in physical abilities, worsened by sedentary lifestyles, which reduce autonomy and quality of life. Public policies must promote “active ageing,” with APA as a key
Di Mare Simona   +3 more
wiley   +1 more source

Twenty‐year results of the randomized European Organization for Research and Treatment of Cancer trial 22922/10925 evaluating internal mammary chain and medial supraclavicular lymph node irradiation in stage I–III breast cancer

open access: yesCA: A Cancer Journal for Clinicians, Volume 76, Issue 3, May/June 2026.
Abstract European Organization for Research and Treatment of Cancer trial EORTC 22922/10925 evaluated internal mammary and medial supraclavicular (IM‐MS) lymph node irradiation (IM‐MS‐RT) in patients with stage I–III breast cancer. Eligible patients had involved axillary nodes and/or centrally/medially located tumors regardless of nodal involvement ...
Orit Kaidar‐Person   +24 more
wiley   +1 more source

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