Results 181 to 190 of about 10,255 (211)
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Cancer Research, 2023
Abstract BACKGROUND: Immune checkpoint inhibitors in combination with chemotherapy have demonstrated an improvement of pathologic complete response (pCR) in patients with HR-HER2- and MammaPrint (MP) High Risk, HR+HER2- tumors in the I-SPY2 TRIAL. However, not all patients benefit from immune checkpoint blockade and these new agents come
Adam M. Brufsky +26 more
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Abstract BACKGROUND: Immune checkpoint inhibitors in combination with chemotherapy have demonstrated an improvement of pathologic complete response (pCR) in patients with HR-HER2- and MammaPrint (MP) High Risk, HR+HER2- tumors in the I-SPY2 TRIAL. However, not all patients benefit from immune checkpoint blockade and these new agents come
Adam M. Brufsky +26 more
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Cancer Research, 2022
Abstract Introduction: Early lymph node (LN) metastasis often precedes systemic metastasis and corresponds with a 35% decrease in 10-year survival compared to patients without LN metastasis. Understanding biologic pathways involved in early LN metastasis could identify promising drug targets for early-stage breast cancer (EBC) treatment.
Nibash Budhathoki +11 more
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Abstract Introduction: Early lymph node (LN) metastasis often precedes systemic metastasis and corresponds with a 35% decrease in 10-year survival compared to patients without LN metastasis. Understanding biologic pathways involved in early LN metastasis could identify promising drug targets for early-stage breast cancer (EBC) treatment.
Nibash Budhathoki +11 more
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Cancer Research, 2023
Abstract FLEX: 30K Full Transcriptome, Real-World Evidence Database for Early-Stage Breast Cancer, and Investigator-Initiated Protocols BACKGROUND: Genomic signatures, such as the 70-gene MammaPrint, provide additional prognostic information for early-stage breast cancer (EBC), such as tumor metastatic potential, and expand the available
Alejandra Perez +11 more
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Abstract FLEX: 30K Full Transcriptome, Real-World Evidence Database for Early-Stage Breast Cancer, and Investigator-Initiated Protocols BACKGROUND: Genomic signatures, such as the 70-gene MammaPrint, provide additional prognostic information for early-stage breast cancer (EBC), such as tumor metastatic potential, and expand the available
Alejandra Perez +11 more
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Cancer Research, 2022
Abstract Introduction: Young women with estrogen receptor (ER)-positive early-stage breast cancer (EBC) frequently present with larger, higher-grade, more aggressive tumors, with lower ER expression than older women. Post-hoc analyses within the MINDACT and TAILORx cohorts reported that women aged 40-50 with ER+ EBC exhibited a ...
Shubhada Dhage +12 more
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Abstract Introduction: Young women with estrogen receptor (ER)-positive early-stage breast cancer (EBC) frequently present with larger, higher-grade, more aggressive tumors, with lower ER expression than older women. Post-hoc analyses within the MINDACT and TAILORx cohorts reported that women aged 40-50 with ER+ EBC exhibited a ...
Shubhada Dhage +12 more
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Adverse Events and Failure Modes Related to Impella RP/RP Flex: Insights From FDA MAUDE Database
Catheterization and Cardiovascular InterventionsABSTRACTBackgroundImpella RP and RP Flex can provide right ventricular (RV) support in numerous clinical situations. Notably, the redesigned RP Flex allows for an internal jugular approach compared to the femoral venous approach with RP.AimsWe investigated the type and frequency of device‐related complications as reported in the US Food and Drug ...
Kalyan R. Chitturi +9 more
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Cancer Research
Abstract TIPS SABCS 2023 A prospective, international, observational, real-world evidence database, and collaborative platform for Investigator-Initiated Studies in Early-Stage Breast Cancer tested with MammaPrint and BluePrint– the FLEX Study Background: Clinical trials have been an invaluable tool in providing improvements in the ...
JJ Alberty-Oller +9 more
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Abstract TIPS SABCS 2023 A prospective, international, observational, real-world evidence database, and collaborative platform for Investigator-Initiated Studies in Early-Stage Breast Cancer tested with MammaPrint and BluePrint– the FLEX Study Background: Clinical trials have been an invaluable tool in providing improvements in the ...
JJ Alberty-Oller +9 more
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Repository of custom R codes to wrangle .lift and .flexttext output of FLEx into a new SFM database to be re-imported into a new FLEx dictionary/lexicon project.
Cokorda Pramartha +5 more
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Cokorda Pramartha +5 more
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2011
Abstract : The objective of this task was to collect data on all landfills owned by the Department of Defense and to use that information to calculate gas production rates in order to determine which sites may be appropriate for the Flex Microturbine. Given the approximate nature of the source data and the gas production models, this material can only ...
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Abstract : The objective of this task was to collect data on all landfills owned by the Department of Defense and to use that information to calculate gas production rates in order to determine which sites may be appropriate for the Flex Microturbine. Given the approximate nature of the source data and the gas production models, this material can only ...
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2016
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