Results 61 to 70 of about 291,860 (287)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Efecto de los pantalones compresivos en la amplitud articulary el rendimiento en el salto vertical [PDF]

, 2012
Objetivo: Este estudio pretende determinar si la compresión provoca cambios mecánicos en el movimiento y se producen incrementos del rendimiento deportivo.
Balius Matas, Xavier, Borràs, Xantal, Drobnic, Franchek   +2 more
core  

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Does pre-operative flexion factor influence the post operative range of motion in total knee arthroplasty

Journal of Orthopedics, Traumatology and Rehabilitation, 2014
Background: Range of motion and flexion are important outcome measures following total knee arthroplasty. Many of the activities of daily living require knee flexion in the range of 45 to 105°.
Ganesh Babu Natarajan, Veera Ram Narayan, Vijayaraghavan   +2 more
doaj   +1 more source

Estudi sobre la morfologia històrica a les declinacions de la llengua llatina. Una visió des de l'indoeuropeu fins a les llengües romàniques [PDF]

, 2016
El present treball tracta un tema de morfologia històrica de la llengua llatina a partir de la flexió nominal. Aquest estudi pretén donar una visió sobre l'evolució de la flexió dels substantius, començant a partir dels primers testimonis de la llengua ...
Torres Trastallino, Carlos, Universitat Autònoma de Barcelona. Facultat de Filosofia i Lletres   +1 more
core  

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Elaboración y caracterización de concreto polimérico: efecto del contenido de fibra de luffa y de la radiación gamma [PDF]

, 2012
A pesar de que el concreto convencional (elaborado con cemento Portland) es un material con gran versatilidad en cuanto a su funcionalidad y economía, presenta algunas limitaciones tales como: alta porosidad y baja resistencia a esfuerzos de flexión ...
MARTINEZ LOPEZ, MIGUEL, MARTINEZ LOPEZ, MIGUEL   +1 more
core  

Valoración de las repercusiones cinemáticas en la extremidad inferior del antepié varo, en niños entre 7 y 10 años [PDF]

, 2010
El objetivo del estudio fue determinar las repercusiones cinemáticas del antepié varo (AV) en un grupo de niños de 7-10 años, tanto en estática como durante la marcha. Población: 30 niños con AV (9.3 ± 1.7 años; 6.1º ± 2.3º de AV), 21 niños control (GC)
Alonso, A., Calvo, B., Franco, M.A., García, I., Villarroya, M.A.   +4 more
core   +2 more sources

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source