Results 321 to 330 of about 5,317,081 (363)

Cognitive and behavioural flexibility: neural mechanisms and clinical considerations

open access: yesNature Reviews Neuroscience, 2021
Cognitive and behavioural flexibility permit the appropriate adjustment of thoughts and behaviours in response to changing environmental demands. Brain mechanisms enabling flexibility have been examined using non-invasive neuroimaging and behavioural ...
Lucina Q Uddin
exaly   +2 more sources

Metabolic Flexibility as an Adaptation to Energy Resources and Requirements in Health and Disease

open access: yesEndocrine Reviews, 2018
The ability to efficiently adapt metabolism by substrate sensing, trafficking, storage, and utilization, dependent on availability and requirement, is known as metabolic flexibility.
Reuben L Smith   +2 more
exaly   +2 more sources

DynaMut: predicting the impact of mutations on protein conformation, flexibility and stability

open access: yesNucleic Acids Research, 2018
Proteins are highly dynamic molecules, whose function is intrinsically linked to their molecular motions. Despite the pivotal role of protein dynamics, their computational simulation cost has led to most structure-based approaches for assessing the ...
Douglas E V Pires, David B Ascher
exaly   +2 more sources

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