Results 101 to 110 of about 4,007,356 (365)

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

Optimizing a human monoclonal antibody for better neutralization of SARS-CoV-2

Nature Communications
SARS-CoV-2 has largely evolved to resist antibody pressure, with each successive viral variant becoming more and more resistant to serum antibodies in the population.
Qian Wang, Yicheng Guo, Ryan G. Casner, Jian Yu, Manoj S. Nair, Jerren Ho, Eswar R. Reddem, Ian A. Mellis, Madeline Wu, Chih-Chen Tzang, Hsiang Hong, Yaoxing Huang, Lawrence Shapiro, Lihong Liu, David D. Ho   +14 more
doaj   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

FEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman, Jessica Haines, Connie Pritchard, Stephen Rutherford, Nigel Francis   +4 more
wiley   +1 more source

Modified Grey Wolf Optimizer for Global Engineering Optimization

Applied Computational Intelligence and Soft Computing, 2016
Nature-inspired algorithms are becoming popular among researchers due to their simplicity and flexibility. The nature-inspired metaheuristic algorithms are analysed in terms of their key features like their diversity and adaptation, exploration and ...
N. Mittal, Urvinder Singh, B. S. Sohi
semanticscholar   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Flexibility in Research Designs in Empirical Software Engineering [PDF]

, 2008
Vigdis By Kampenes, Bente Anda, Tore Dybå   +2 more
openalex   +1 more source

Flexible multilayer lead-free film capacitor with high energy storage performances via heterostructure engineering

, 2022
Ningning Sun, Jinhua Du, Ye Zhao, Chunxiao Lü, Pei Han, Yong Li, Qiwei Zhang, Xihong Hao   +7 more
openalex   +1 more source

Digital Typography in the New Millennium: Flexible Documents by a Flexible Engine

, 2004
The TEX family of electronic typesetters contains the primary typesetting tools for the preparation of demanding documents, and have been in use for many years. However, our era is characterized, among others, by Unicode, XML and the introduction of interactive documents.
Loverdos, C.K.K., Syropoulos, A.
openaire   +2 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Investigation of effect of processing parameters of 3D printed NHS/EDC crosslinked carboxy methyl cellulose/gelatin hydrogels with machine learning techniques

Materials Research Express
This study focuses on the effects of preparing conditions of gelatin/carboxymethyl cellulose (CMC) composites on their mechanical properties of gelatin/carboxymethyl cellulose (CMC) by extreme gradient boosting (XGB) machine learning algorithm.
Duygu Ege, Şule Arıcı
doaj   +1 more source