Results 61 to 70 of about 1,173,607 (300)

Practical application of CFD for wind loading on tall buildings [PDF]

open access: yes, 2009
This paper is concerned with assessing the scope of appicabiity for computational fluid dynamics(CFD) in the field of structural engineering, with a particular reference to tall buildings.
Bicanic, N.   +4 more
core   +2 more sources

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Nanoscale Interfacial Engineering for Flexible Barrier Films

open access: yesNano Letters, 2015
Alternating layers of organic and oxide thin films used as diffusion barriers in emerging flexible device technologies are vulnerable to degradation under the influence of mechanical stresses, temperature cycling, photodegradation, and chemically active environmental species.
Can, Cai, Reinhold H, Dauskardt
openaire   +3 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Flexibility features in patent writing [PDF]

open access: yesIbérica, 2012
International patents are increasingly demanded in academic circles as a sign of excellence and compete with situated genres such as projects, grants, PhD supervisions, books and journal articles, especially in hard science environments.
Carmen Sancho-Guinda
doaj  

Effect of non-repetitive linker on in vitro and in vivo properties of an anti-VEGF scFv

open access: yesScientific Reports, 2022
Single chain antibody fragments (scFvs) are favored in diagnostic and therapeutic fields thanks to their small size and the availability of various engineering approaches.
Merve Arslan   +5 more
doaj   +1 more source

Type Inference in Flexible Model-Driven Engineering [PDF]

open access: yes, 2015
In Model-Driven Engineering (MDE), models conform to metamodels. In flexible modelling, engineers construct example models with free-form drawing tools; these examples may later need to conform to a metamodel. Flexible modelling can lead to errors: drawn elements that should represent the same domain concept could instantiate different types; other ...
Zolotas, Athanasios   +4 more
openaire   +2 more sources

Multidisciplinary Engineering: Flexibility And Abet Accreditation [PDF]

open access: yes2009 Annual Conference & Exposition Proceedings, 2020
Comment: 19 ...
Phillip Wankat, Kamyar Haghighi
openaire   +2 more sources

Evaluation of the effectiveness of online video screening process in a regional city council: Specifically evaluating the fairness of the system [PDF]

open access: yes, 2018
In the past few years, a regional City Council has seen the increasing importance of online video screening platforms like Sonru speed up the current recruitment process.
Griarte, Janica, Taylor, Beverly
core  

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