Results 81 to 90 of about 4,007,356 (365)

HACS: A Hybrid Framework for Continuous Flexible and Controlled Architecting

Acta Informatica Pragensia, 2017
Systems like e-voting, e-banking or e-health must offer flexibility to continuously meet technical and legal changing requirements and must at the same time guarantee robustness to respect their security and sensitivity.
Bentlemsan Khadidja, Bennouar Djamel, Tamzalit Dalila, Hidouci Khaled Walid   +3 more
doaj   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Integration of Multiple Heterointerfaces in a Hierarchical 0D@2D@1D Structure for Lightweight, Flexible, and Hydrophobic Multifunctional Electromagnetic Protective Fabrics

Nano-Micro Letters, 2023
Highlights Electrospinning combined with structural engineering to construct 0D@2D@1D hierarchical heterogeneous interfaces. A “mechanical response” model was constructed to explain the stress transfer mechanism of fibrous membranes with 2D@1D structures.
Shuo Zhang, Xuehua Liu, Chenyu Jia, Zhengshuo Sun, Haowen Jiang, Zirui Jia, Guanglei Wu   +6 more
doaj   +1 more source

Absorbing stress via molecular crumple zones: Strain engineering flexibility into the rigid UiO-66 material [PDF]

, 2023
Sven M. J. Rogge, Sander Borgmans, Véronique Van Speybroeck   +2 more
openalex   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

DAMAGE DETECTION OF BEAM STRUCTURE USING DERIVED SENSITIVITY BASED ON STRUCTURAL FLEXIBILITY

Jixie qiangdu, 2017
The flexibility-based damage identification methods have attracted much attention in structural engineering field in recent years. In this paper,three derived sensitivity methods based on structural flexibility are presented for damage identification ...
ZHAO JingYun, YANG QiuWei, LI CuiHong, ZHANG Ying, LIANG ChaoFeng   +4 more
doaj  

An Embedded Control System for a 3D-Printed Robot for Training

Engineering Proceedings
This study explores the application of 3D printing as a strategic tool in engineering education and robotics development. An embedded control system for a 3D-printed MK2 manipulator is implemented, including an Arduino microcontroller, servo motors, an ...
Zhelyazko Terziyski, Nikolay Komitov, Margarita Terziyska   +2 more
doaj   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Advancing Topological Interlocking Structures: Recent Developments, Applications, and Challenges in Civil Engineering

International Journal of Concrete Structures and Materials
Topological interlocking structures have garnered significant attention for their distinctive properties, including robust resistance to crack propagation, outstanding energy absorption, adaptable flexibility, high resistance to missing elements and easy
Maliheh Tavoosi Gazkoh, Xiaoshan Lin, Annan Zhou   +2 more
doaj   +1 more source