Results 61 to 70 of about 8,102,967 (335)
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
An SDN-based Approach For Defending Against Reflective DDoS Attacks
, 2018 Distributed Reflective Denial of Service (DRDoS) attacks are an immanent threat to Internet services. The potential scale of such attacks became apparent in March 2018 when a memcached-based attack peaked at 1.7 Tbps.
Erb, Benjamin +4 more
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
IEEE Access, 2023 Unlocking flexibility assets from the consumer side and developing a well-functioning flexibility market (FM) is crucial to address the oncoming challenges in the EU power grid. In these conditions, the coordination between distribution system operators (
Damian Sieraszewsk +4 more
doaj +1 more source
Scenario-Based Stochastic Optimization for Energy and Flexibility Dispatch of a Microgrid
IEEE Transactions on Smart Grid, 2022 Energy storage is one of the most important components of microgrids with non-dispatchable generators and can offer both energy and flexibility services when the microgrid operates in grid-connected mode.
K. Antoniadou-Plytaria +5 more
semanticscholar +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
IEEE AccessDue to large-scale integration of variable renewable generation and accelerating electrification of transportation and heating sectors as well as industrial processes, increased amount of flexibility is needed from different voltage levels to fulfill ...
Hannu Laaksonen +2 more
doaj +1 more source
Cloud Computing in the Quantum Era [PDF]
, 2019 Cloud computing has become the prominent technology of this era. Its elasticity, dynamicity, availability, heterogeneity, and pay as you go pricing model has attracted several companies to migrate their businesses' services into the cloud.
Kaiiali, Mustafa +2 more
core +2 more sources
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Cogent Business & Management, 2022 This study aims to develop rules of thumb for the financial conditions of city livability. These rules will provide a practical guide for local government leaders managing local government finances on how to realize a livable city.
Irwan Taufiq Ritonga +1 more
doaj +1 more source