Results 101 to 110 of about 1,375 (234)

ER proteostasis meets mitochondrial function: contact sites as hubs of communication and therapeutic targets

The FEBS Journal, EarlyView.
Proteostasis ensures proper protein folding, modification, and degradation, while its impairment triggers ER stress. Chronic ER stress and maladaptive UPR via the CHOP–ERO1 axis remodel ERMCs, altering calcium signaling and mitochondrial metabolism.
Giorgia Maria Renna, Alessandro Cherubini, Ersilia Varone, Serena Germani, Alice Marrazza, Ester Zito   +5 more
wiley   +1 more source

Expanding the Fish‐Brain Invitrome With the Senegalese Sole SsB‐1 Cell Line—A Versatile Model for Neurotropic Virus Research

Journal of Fish Diseases, EarlyView.
ABSTRACT Cell lines are essential tools for studying animal physiology and immunopathology, reducing the use of live animals and supporting the 3Rs principle of reduction, refinement, and replacement. The Senegalese sole (Solea senegalensis), a relevant species for Spanish aquaculture diversification, lacks established in vitro models. We developed SsB‐
Yulema Valero, Alberto Cuesta
wiley   +1 more source

How do forelimb long bones adapt in rhinoceroses? An in‐depth examination of their microanatomy

Journal of Anatomy, EarlyView.
Here, we study the bone structure in the forelimb long bones of the five extant species of rhinoceroses. By combining traditional description of virtual sections made on the bones (A) with in‐depth cartographies of the variation of bone compactness and anisotropy (B), we show how bone tissue can adapt to extreme forces and constraints in the second ...
Cyril Etienne, Axel de Jesus, Vincent Fernandez, Alexandra Houssaye   +3 more
wiley   +1 more source

A description of dental microanatomy and implantation geometry in Chamaeleonidae

Journal of Anatomy, EarlyView.
A reassessment of the dental histology in adult chamaeleons reveals the presence of periodontal ligament. Alongside alveolar bone and cementum, these tissues together constitute a compacted and remodelled tripartite periodontium. Our findings include the novel observation of plicidentine‐like protuberances of dentine within underlying bone.
Giles D. Sukkert, Ilaria Paparella, Michael R. Doschak, Aaron R. H. LeBlanc, Michael W. Caldwell   +4 more
wiley   +1 more source

Local Elites in Chile's Pisco Valley: Dispossession, Legal Mobilisation and Intertwined Citizenship

Journal of Agrarian Change, EarlyView.
ABSTRACT In countries in the Global South, citizenship is often closely tied to access to water and land ownership. In Latin America, the literature has primarily explored social mobilisation and identity reconfiguration in response to development‐driven processes of land and water dispossession affecting peasants, rural and Indigenous communities ...
Chloé Nicolas‐Artero
wiley   +1 more source

Bridging Knowledge Capability Gaps: Digital Technology Offsetting in Interfirm Knowledge Transfer

Journal of Management Studies, EarlyView.
Abstract In this digital age, the adoption of digital technology (DT) is changing traditional business processes. Against this backdrop, we try to answer the question of whether DT could effectively bridge any interfirm knowledge capability gaps. Though effective knowledge transfer is dependent on the sender's and the receiver's knowledge capabilities,
Antony Paulraj, Chandrasekararao Seepana, Murtaza Faruquee, Vaidyanathan Jayaraman   +3 more
wiley   +1 more source

Engineered surface strategies to manage dental implant‐related infections

Periodontology 2000, EarlyView.
Abstract When exposed to the oral environment, dental implants, like natural surfaces, become substrates for microbial adhesion and accumulation, often leading to implant‐related infections—one of the main causes of implant failure. These failures impose significant costs on patients, clinicians, and healthcare systems.
João Gabriel S. Souza, Bruna E. Nagay, Rodrigo Martins, Martinna Bertolini, Jamil A. Shibli, Conrado Aparicio, Magda Feres, Valentim A. R. Barão   +7 more
wiley   +1 more source

Is acquisition‐related foreign direct investment during an economic crisis detrimental for domestic innovation?

The Scandinavian Journal of Economics, EarlyView.
Abstract We study how acquisition‐related foreign direct investment during economic crises affects R&D investments and the direction of innovation of target firms, compared with acquisitions made during periods of strong economic growth. Using a panel of Spanish firms, we find that foreign multinationals cherry‐pick the best domestic firms ...
María García‐Vega, Apoorva Gupta, Richard Kneller   +2 more
wiley   +1 more source

Changes in motor unit conduction velocity after unilateral lower‐limb suspension and active recovery are correlated with muscle ion channel gene expression

Experimental Physiology, EarlyView.
Abstract The effects of muscle disuse on the propagation of action potentials along motor unit (MU) muscle fibres, a key process for effective muscle activation and force generation, remain poorly understood. The aim of this study was to investigate changes in action potential propagation and to identify biological factors influencing these changes ...
Giacomo Valli, Fabio Sarto, Francesco Negro, Elena Monti, Giuseppe Sirago, Matteo Paganini, Sandra Zampieri, Martino V. Franchi, Andrea Casolo, Julián Candia, Luigi Ferrucci, Marco V. Narici, Giuseppe De Vito   +12 more
wiley   +1 more source

Faecal Microbiota Transplantation in Anorexia Nervosa: A Systematic Review of Methodologies, Outcomes, and Challenges With Recommendations for Future Studies

European Eating Disorders Review, Volume 34, Issue 4, Page 926-945, July 2026.
ABSTRACT Objective Anorexia nervosa (AN) is a severe psychiatric disorder displaying an altered gut microbiome. Faecal microbiome transplantation (FMT) has emerged as a powerful research tool and potential treatment option in AN due to the microbiome‐gut‐brain axis. Current studies are limited and reveal variable FMT protocols.
Anna C. Thelen, Nele M. Korten, Larissa Blischke, Clara Voelz, Cordian Beyer, Jochen Seitz, Stefanie Trinh   +6 more
wiley   +1 more source