Results 141 to 150 of about 80,748 (270)

ER proteostasis meets mitochondrial function: contact sites as hubs of communication and therapeutic targets

open access: yesThe FEBS Journal, EarlyView.
Proteostasis ensures proper protein folding, modification, and degradation, while its impairment triggers ER stress. Chronic ER stress and maladaptive UPR via the CHOP–ERO1 axis remodel ERMCs, altering calcium signaling and mitochondrial metabolism.
Giorgia Maria Renna   +5 more
wiley   +1 more source

Lack of Lumpfish (Cyclopterus lumpus) Susceptibility to the Infectious Salmon Anaemia Virus (ISAV) Using In Vivo Challenges

open access: yesJournal of Fish Diseases, EarlyView.
ABSTRACT Infectious salmon anaemia virus (ISAV) can cause disease and mortality in Atlantic salmon (Salmo salar). The virus is endemic in several regions including the Atlantic coast of Canada. Lumpfish (Cyclopterus lumpus) are increasingly utilised as cleaner fish to control sea lice levels in Atlantic salmon farms.
Nellie Gagné   +5 more
wiley   +1 more source

Expanding the Fish‐Brain Invitrome With the Senegalese Sole SsB‐1 Cell Line—A Versatile Model for Neurotropic Virus Research

open access: yesJournal of Fish Diseases, EarlyView.
ABSTRACT Cell lines are essential tools for studying animal physiology and immunopathology, reducing the use of live animals and supporting the 3Rs principle of reduction, refinement, and replacement. The Senegalese sole (Solea senegalensis), a relevant species for Spanish aquaculture diversification, lacks established in vitro models. We developed SsB‐
Yulema Valero, Alberto Cuesta
wiley   +1 more source

Local Elites in Chile's Pisco Valley: Dispossession, Legal Mobilisation and Intertwined Citizenship

open access: yesJournal of Agrarian Change, EarlyView.
ABSTRACT In countries in the Global South, citizenship is often closely tied to access to water and land ownership. In Latin America, the literature has primarily explored social mobilisation and identity reconfiguration in response to development‐driven processes of land and water dispossession affecting peasants, rural and Indigenous communities ...
Chloé Nicolas‐Artero
wiley   +1 more source

Bridging Knowledge Capability Gaps: Digital Technology Offsetting in Interfirm Knowledge Transfer

open access: yesJournal of Management Studies, EarlyView.
Abstract In this digital age, the adoption of digital technology (DT) is changing traditional business processes. Against this backdrop, we try to answer the question of whether DT could effectively bridge any interfirm knowledge capability gaps. Though effective knowledge transfer is dependent on the sender's and the receiver's knowledge capabilities,
Antony Paulraj   +3 more
wiley   +1 more source

Engineered surface strategies to manage dental implant‐related infections

open access: yesPeriodontology 2000, EarlyView.
Abstract When exposed to the oral environment, dental implants, like natural surfaces, become substrates for microbial adhesion and accumulation, often leading to implant‐related infections—one of the main causes of implant failure. These failures impose significant costs on patients, clinicians, and healthcare systems.
João Gabriel S. Souza   +7 more
wiley   +1 more source

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