Results 41 to 50 of about 905 (139)

MEK Inhibitor Associated Airway Injury in an Infant With Noonan Syndrome: A Case Report

The Laryngoscope, EarlyView.
An infant with Noonan syndrome treated with trametinib developed extensive mucosal sloughing of the upper and lower airway, followed by severe supraglottic scarring. Clinicians should consider airway toxicity as a potential adverse effect of MEK inhibitor therapy.
Veronica Drozdowski‐Nuccio, Rachel D. Yoon, Steven Tomasi, Dana M. Thompson, Inbal Hazkani   +4 more
wiley   +1 more source

Inter‐ and Intra‐Rater Reliability of 4D‐CT Versus Bronchoscopy in Diagnosing and Grading Tracheomalacia

The Laryngoscope, EarlyView.
Bronchoscopy and 4D‐CT are used to grade tracheomalacia severity, though reliability across raters and specialties has been unclear. In this multi‐institutional, multidisciplinary survey study, endoscopic assessment showed higher inter‐ and intra‐rater reliability than 4D‐CT, though both modalities demonstrated substantial‐to‐almost‐perfect agreement ...
Hannah F. Case, Shaunak Amin, Xing Wang, Michael Barbour, Michael Bindschadler, Tanya Meyer, Seth Friedman, Alberto Aliseda, John P. Dahl, Randall A. Bly   +9 more
wiley   +1 more source

Evaluating the Local Response of a Novel Injectable Capsule for Drug Delivery in the Trachea

The Laryngoscope, EarlyView.
A novel PLGA polymer capsule was developed for localized pretracheal drug delivery and evaluated for short‐term local tissue safety in a rabbit model. Implant placement was confirmed by ultrasound and was well tolerated over 14 days, with preservation of airway patency, native tracheal architecture, and biomechanical properties.
Denzel Ryan D. Cruz, Nour Awad, Nicholas Russell, Juliana El Sheikh, Logan Obermeyer, Peter J. Larson, Yoonjee C. Park, Gregory R. Dion   +7 more
wiley   +1 more source

Congenital Intraoral Synechiae: A Scoping Review of Airway, Feeding, and Surgical Management

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To map the existing literature on congenital intraoral synechiae and summarize reported anatomic patterns, clinical presentation, associated anomalies/syndromes, and outcomes to inform standardized diagnostic and therapeutic approaches. Data Sources PubMed, CINAHL, Embase, Web of Science, and Google Scholar were searched from January
Jason Bernier, Mathieu Bergeron
wiley   +1 more source

Subglottic jet ventilation versus supraglottic jet ventilation for flexible bronchoscopy: a randomized controlled trial

BMC Anesthesiology
Background Jet ventilation technique can be used to supply oxygen to prevent hypoxia for patients undergoing flexible bronchoscopy. An optimal access route for jet ventilation technique during flexible bronchoscopy has not been determined. Our aim was to
Chunlan Lin, Chenglong Zhu, Liangqing Lin, Qinghua Wu, Huan Chen, Tingting Zou, Hai Chen, Zui Zou, Yaohua Yu   +8 more
doaj   +1 more source

Diagnostic Yield of EBUS Mediastinal Cryobiopsy Versus TBNA in Suspected Lymphoproliferative Disorders: A Prospective Multicentre Study

Respirology, EarlyView.
We assessed the diagnostic yield of EBUS‐guided transbronchial mediastinal cryobiopsy (EBUS‐TBMC) compared with EBUS‐transbronchial needle aspiration (EBUS‐TBNA) in patients with suspected mediastinal lymphoproliferative disorders (LPDs). EBUS‐TBMC was superior to EBUS‐TBNA and achieved a high diagnostic yield in patients with suspected mediastinal ...
Yaniv Dotan, Ayal Romem, Elad Guber, Michael Kassirer, Daphne Felus, Nimrod Urtreger, Ophir Freund, Hanna A. Dawood, Boaz Tiran, Doron Cohn‐Schwartz, Sarah Borsekofsky, Amir Bar‐Shai, Evgeni Gershman   +12 more
wiley   +1 more source

Dysphagia in Children With Autism Spectrum Disorder: A Scoping Review

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective There are four phases of swallowing: oral preparatory, oral transit, oropharyngeal, and esophageal. Disruption of any phase(s) can lead to dysphagia. Autism spectrum disorder (ASD) children have a high rate of dysphagia compared with neurotypical peers.
Chase Hintelmann, Sharwani Kota, Pamela Hargwood, Lilun Li   +3 more
wiley   +1 more source

Histopathological patterns of endobronchial lesions and the role of flexible fiberoptic bronchoscopy in their diagnosis

Al-Azhar Assiut Medical Journal, 2020
Background Flexible bronchoscopy has become the most commonly used invasive procedure in pulmonary medicine used for diagnosis of multiple lesions of respiratory system presenting as endobronchial mass lesions, either benign or malignant in nature.
Khaled M Halima, Sameh F Makled, Fareed S Basiony   +2 more
doaj   +1 more source

Effect of Dupilumab on Airway Inflammation in Patients With Persistent Asthma

Allergy, EarlyView.
EXPEDITION (NCT02573233) assessed the effects of dupilumab on airway inflammation in patients with persistent asthma using bronchoscopy and gene expression analysis. Dupilumab showed no appreciable effect on inflammatory cell types in biopsies or BALF samples.
Michael E. Wechsler, Sally E. Wenzel, Steve D. Groshong, Mario Castro, Ian D. Pavord, Klaus F. Rabe, Elizabeth Laws, Alexandre Jagerschmidt, Kaitlyn Gayvert, Sivan Harel, Jennifer D. Hamilton, Nikhil Amin, Lu Zhang, Heming Xing, Anissa Elfakir, Bema Coulibaly, Souâd Naimi, Sara Hamon, Paul J. Rowe, Frank Nestle, Danen M. Cunoosamy, Emanuele de Rinaldis, Leda P. Mannent   +22 more
wiley   +1 more source

Guidelines for diagnostic flexible bronchoscopy in adults: Joint Indian Chest Society/National College of chest physicians (I)/Indian association for bronchology recommendations

Lung India, 2019
Flexible bronchoscopy (FB) is commonly performed by respiratory physicians for diagnostic as well as therapeutic purposes. However, bronchoscopy practices vary widely across India and worldwide.
Anant Mohan, Karan Madan, Vijay Hadda, Pawan Tiwari, Saurabh Mittal, Randeep Guleria, G C Khilnani, S K Luhadia, R N Solanki, K B Gupta, Rajesh Swarnakar, S N Gaur, Pratibha Singhal, Irfan Ismail Ayub, Shweta Bansal, Prashu Ram Bista, Shiba Kalyan Biswal, Ashesh Dhungana, Sachin Doddamani, Dilip Dubey, Avneet Garg, Tajamul Hussain, Hariharan Iyer, Venkatnarayan Kavitha, Umasankar Kalai, Rohit Kumar, Swapnil Mehta, Vijay Noel Nongpiur, N Loganathan, P B Sryma, Raju Prasad Pangeni, Prajowl Shrestha, Jugendra Singh, Tejas Suri, Sandip Agarwal, Ritesh Agarwal, Ashutosh Nath Aggarwal, Gyanendra Agrawal, Suninder Singh Arora, Balamugesh Thangakunam, D Behera, Jayachandra, Dhruva Chaudhry, Rajesh Chawla, Rakesh Chawla, Prashant Chhajed, Devasahayam J Christopher, M K Daga, Ranjan K Das, George D'Souza, Raja Dhar, Sahajal Dhooria, Aloke G Ghoshal, Manoj Goel, Bharat Gopal, Rajiv Goyal, Neeraj Gupta, N K Jain, Neetu Jain, Aditya Jindal, S K Jindal, Surya Kant, Sandeep Katiyar, S K Katiyar, Parvaiz A Koul, Jaya Kumar, Raj Kumar, Ajay Lall, Ravindra Mehta, Alok Nath, V R Pattabhiraman, Dharmesh Patel, Rajendra Prasad, J K Samaria, Inderpaul Singh Sehgal, Shirish Shah, Girish Sindhwani, Sheetu Singh, Virendra Singh, Rupak Singla, J C Suri, Deepak Talwar, T K Jayalakshmi, T P Rajagopal   +83 more
doaj   +1 more source