Results 81 to 90 of about 228,732 (306)
A modular FPGA-based ultrasonic array system for applications including non-destructive testing [PDF]
, 2008 This paper reports work aimed at the development of an ultrasonic imaging system comprising modular, reprogrammable building blocks, or tiles, which can be customised for multiple applications, including and within non-destructive testing (NDT), by the ...
Afroukh, F. +6 more
core +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Structural Dynamics, 2018 We present a flexible and efficient ultrafast time-resolved spontaneous Raman spectroscopy setup to study collective excitation and quasi-particle dynamics in quantum materials. The setup has a broad energy tuning range extending from the visible to near
R. B. Versteeg +7 more
doaj +1 more source
Temperature dependence of circular DNA topological states
, 2009 Circular double stranded DNA has different topological states which are defined by their linking numbers. Equilibrium distribution of linking numbers can be obtained by closing a linear DNA into a circle by ligase.
Chen, Hu +5 more
core +1 more source
Polymer nanofibers as novel light-emitting sources and lasing material [PDF]
, 2013 Polymer micro- and nano-fibers, made of organic light-emitting materials with optical gain, show interesting lasing properties. Fibers with diameters from few tens of nm to few microns can be fabricated by electrospinning, a method based on electrostatic
Camposeo, Andrea +2 more
core +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
The emotional gatekeeper: a computational model of attentional selection and suppression through the pathway from the amygdala to the inhibitory thalamic reticular nucleus [PDF]
, 2016 In a complex environment that contains both opportunities and threats, it is important for an organism to flexibly direct attention based on current events and prior plans. The amygdala, the hub of the brain's emotional system, is involved in forming and
Barbas, Helen +3 more
core +2 more sources
Intercompartmental communication in senescence
FEBS Open Bio, EarlyView.Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz +3 more
wiley +1 more source
Collisional-Radiative Model for the visible spectrum of $W^{26+}$ ions
, 2015 Plasma diagnostics in magnetic confinement fusion plasmas by using visible spectrum strongly depends on the knowledge of fundamental atomic properties. A detailed collisional-radiative model of W$^{26+}$ ions has been constructed by considering radiative
Ding, Xiaobin +7 more
core +1 more source