Results 191 to 200 of about 7,585,843 (289)

A Unified Hierarchical Multiscale Fusion Framework for Drug–Target Affinity Prediction: From Benchmark Performance to Nanomolar Inhibitor Discovery

Advanced Science, EarlyView.
A multimodal fusion framework integrating sequence, atomic, and fragment representations captures drug–target interactions across multiple scales. The model delivers strong predictive performance and enables efficient virtual screening. Applied to hematopoietic progenitor kinase 1 (HPK1), it identifies structurally diverse inhibitors with nanomolar ...
Shuo Liu, Xiang Zhang, Haixia Feng, Yuquan Li, Xiaoqing Gong, Yong Liang, Xiaojun Yao, Huanxiang Liu   +7 more
wiley   +1 more source

An event-driven hybrid rescheduling approach for integrated process planning and scheduling considering stochastic rework. [PDF]

Sci Rep
Shi S, Liu C, Yin L, Xiong H, Xu F, Li C, Liu Y.   +6 more
europepmc   +1 more source

From Sensing Mechanisms to System Co‐Design: Graphene‐Based Sensors and Readout Circuits

Advanced Science, EarlyView.
This review establishes a unified PS–EQ–RF framework linking graphene sensing mechanisms, native electrical outputs, and output‐specific readout circuits. Voltage‐, current‐, resistance‐, and capacitance‐type sensing systems are systematically classified to guide architecture selection, low‐noise design, system co‐design, and practical integration ...
Jinduo Zhang, Meng Chen, Guanchen Li, Ruifeng Liu, Yingxin Wang, Ziran Zhao   +5 more
wiley   +1 more source

Evaluating Bio-Inspired Metaheuristics for Dynamic Surgical Scheduling: A Resilient Three-Stage Flow Shop Model Under Stochastic Emergency Arrivals. [PDF]

Biomimetics (Basel)
Becerra-Rozas M, Gana B, Lara J, Leiva-Araos A, Crawford B, Gómez Pulido JM, Contreras C, Caro-Miranda JJ, García-Remesal M.   +8 more
europepmc   +1 more source

Triple‐Level Content‐Addressable Vertical NAND Flash Memory

Advanced Science, EarlyView.
Commercial triple‐level‐cell V‐NAND flash memory is transformed into a compact content‐addressable memory by directly exploiting its eight threshold‐voltage states. A parity‐split search scheme preserves storage density while enabling reliable multi‐level and don't‐care matching. Parallel word‐line search delivers up to 24‐fold higher throughput and 54.
Sung‐Ho Park, Jiseong Im, Yeongheon Yang, Ryun‐Han Koo, Jonghyun Ko, Mingyun Oh, Dongbeen Shin, Gyuweon Jung, Jong‐Ho Lee   +8 more
wiley   +1 more source

Fuzzy-based multi-objective scheduling for human-robot manufacturing systems. [PDF]

Sci Rep
Deng Y, Huang B, Lai S.
europepmc   +1 more source

Programmable Sequential 4D Actuation in Multistable Kirigami Metamaterials

Advanced Science, EarlyView.
This study presents a modular kirigami metamaterial framework enabling programmable multistability and sequential 4D actuation. By coupling geometry‐controlled multistability with material‐dependent recovery kinetics, spatiotemporal deformation can be precisely programmed.
Eui‐Hyun Kim, Minsung Kim, Hyunsik Yoon, Keun Park   +3 more
wiley   +1 more source

Energy-efficient scheduling of AGV-assisted robotic flexible flowshops under learning and processing time uncertainty. [PDF]

Sci Rep
Dehnavi S, Mokhtari H, Rezvan MT.
europepmc   +1 more source

DyProL: Dynamic Ensemble Representation Learning for Protein–Nucleic Acid Binding Site Prediction

Advanced Science, EarlyView.
Protein function is represented as a dynamic conformational ensemble rather than a single static structure. A multi‐conformation geometric attention framework aligns, clusters, and learns representative states to capture residue‐ and ensemble‐level signals. Integrating structural dynamics improves interpretable protein‐NA binding prediction and reveals
Pengpai Li, Yiman Liu, Liya Liang, Rongming Liu   +3 more
wiley   +1 more source

Research on scheduling optimization of ship plate processing workshop based on improved NSGA-II algorithm. [PDF]

Sci Rep
Dong L, Liu J, Gu S, Li S, Jiang R, Yang H, Cheng Z.   +6 more
europepmc   +1 more source