Results 51 to 60 of about 1,810,420 (307)

Energy-Efficient Last-Mile Logistics Using Resistive Grid Path Planning Methodology (RGPPM)

Energies
Last-mile logistics is a critical operational and environmental challenge in urban areas. This paper introduces an intelligent path planning system using the Resistive Grid Path Planning Methodology (RGPPM) to optimize distribution based on energy and ...
Carlos Hernández-Mejía, Delia Torres-Muñoz, Carolina Maldonado-Méndez, Sergio Hernández-Méndez, Everardo Inzunza-González, Carlos Sánchez-López, Enrique Efrén García-Guerrero   +6 more
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Wage setting and wage flexibility in Ireland - Results from a firm-level survey [PDF]

This paper investigates the wage-setting behaviour of Irish firms. We place particular emphasis on the use of flexible pay components and examine how these allow firms to deal with shocks requiring a reduction in costs without having to cut base wages ...
Keeney, Mary, Lawless, Martina
core   +3 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Fully Biobased Epoxy Resins from Fatty Acids and Lignin

Molecules, 2020
The use of renewable resources for plastic production is an imperious need for the reduction of the carbon footprint and the transition towards a circular economy.
Pablo Ortiz, Richard Vendamme, Walter Eevers   +2 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

FREE STONE FREQUENCY AFTER PERCUTANEOUS NEPHROSTOLITHOMI WITH FLEXIBLE NEPHROSCOPE

Journal of Research in Medical Sciences, 2003
Introduction: The prevalence of urinary stones is 2-3"10.Therefore well treatment of the stones is vwre important PCNL is the new method sor excluding the stones from kidney with minimal pain, convalescence, convalescence, complications and cost.
M HATEF KHORRAMI, M KABIRI, MARYAM AMINI
doaj  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Developed Time-Varying Delay-Determination and Reaching Law for Internal Model Sliding Mode Control in Flexible Mechanical Systems

IEEE Access
Flexible mechanical systems frequently operate under uncertainties, including time-varying delays resulting from flexible structures and external disturbances.
Mehmet Ugur Soydemir, Savas Sahin
doaj   +1 more source

Empirical Assessment of Inflation Targeting (Analysis of Selected Economic Statistics) [PDF]

, 2013
Inflation Targeting (IT) is used by about 30 countries (both developed and developing countries) around the world, and the number of countries was said to increase (IMF 2005). IT strategy was created as a way of getting inflation under control.
Walerysiak, Grzegorz
core   +2 more sources