Results 111 to 120 of about 8,142,265 (256)

CHOICE OF FLEXIBLE FUNCTIONAL FORMS: REVIEW AND APPRAISAL [PDF]

open access: yes
Choice between alternative flexible functional forms has received little explicit treatment in many empirical agricultural studies. Theoretical criteria and empirical techniques for choosing between flexible functional forms are reviewed.
Thompson, Gary D.
core  

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Flexible Multistage Demand System Based on Indirect Separability, A [PDF]

open access: yes
The notion of indirect separability is exploited to derive a new multistage demand system. The model allows a consistent parameterization of demand relations at various budgeting stages and it fulfills the requirement of flexibility while satisfying ...
Moschini, GianCarlo
core  

Exploring Wave–Vegetation Interaction at Stem Scale: Analysis of the Coupled Flow–Structure Interactions Using the SPH-Based DualSPHysics Code and the FEA Module of Chrono

open access: yesJournal of Marine Science and Engineering
Aquatic vegetation in the littoral zone plays a crucial role in attenuating wave energy and protecting coastal communities from hazardous events. This study contributes to the development of numerical models aimed at designing nature-based coastal ...
Joe El Rahi   +8 more
doaj   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

A CFD-DEM-FEM framework for sediment-laden free-surface flow interacting with flexible structures

open access: yesEngineering Applications of Computational Fluid Mechanics
Coastal and offshore protective structures are often loaded by free-surface flows that carry sediment. This study develops a three-phase numerical framework that couples Computational Fluid Dynamics (CFD), the Discrete Element Method (DEM), and the ...
Zhuolin Su   +4 more
doaj   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Flexible Fertigungssysteme Vortraege, Arbeitsplatzbeschreibungen

open access: yes, 1983
SIGLETIB: RO 4301 (1983)+a / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische ...
Stuttgart Univ. (Germany). Sonderforschungsbereich 155 - Fertigungstechnik - Flexible Fertigungssysteme   +2 more
core  

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