Results 61 to 70 of about 2,402,993 (303)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Stereoisomer-Independent Stable Blue Emission in Axial Chiral Difluorenol

Frontiers in Chemistry, 2021
Bulky conjugated molecules with high stability are the prerequisite for the overall improvement of performance in wide-bandgap semiconductors. Herein, a chiral difluorenol, 2,2′-(9,9′-spirobi[fluorene]-2,2′-diyl)bis(9-(4-(octyloxy)phenyl)-9H-fluoren-9-ol)
Mengna Yu, Xiong Jia, Dongqing Lin, Xue Du, Dong Jin, Ying Wei, Linghai Xie, Linghai Xie, Wei Huang, Wei Huang   +9 more
doaj   +1 more source

Deferred Action: Theoretical model of process architecture design for emergent business processes [PDF]

, 2007
E-Business modelling and ebusiness systems development assumes fixed company resources, structures, and business processes. Empirical and theoretical evidence suggests that company resources and structures are emergent rather than fixed.
Patel, NV
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Active Matrix Flexible Sensory Systems: Materials, Design, Fabrication, and Integration

Advanced Intelligent Systems, 2022
A variety of modern applications including soft robotics, prosthetics, and health monitoring devices that cover electronic skins (e‐skins), wearables as well as implants have been developed within the last two decades to bridge the gap between artificial
Bin Bao, Dmitriy D. Karnaushenko, Oliver G. Schmidt, Yanlin Song, Daniil Karnaushenko   +4 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Unveiling the Effects of Interchain Hydrogen Bonds on Solution Gelation and Mechanical Properties of Diarylfluorene-Based Semiconductor Polymers

Research, 2020
The intrinsically rigid and limited strain of most conjugated polymers has encouraged us to optimize the extensible properties of conjugated polymers.
Lubing Bai, Yamin Han, Chen Sun, Xiang An, Chuanxin Wei, Wei Liu, Man Xu, Lili Sun, Ning Sun, Mengna Yu, He Zhang, Qi Wei, Chunxiang Xu, Yingguo Yang, Tianshi Qin, Linghai Xie, Jinyi Lin, Wei Huang   +17 more
doaj   +1 more source

ENTROPY FLEXIBILITY OF DYNAMICAL SYSTEMS

Inspired by Katok's intermediate entropy property [Inst. Hautes Études Sci. Publ. Math. 51 (1980), 137-173], we introduce and study the notion of entropy flexibility for discrete-time and continuous-time dynamical systems. By using renewal systems techniques, we show that this property is present in several classes of systems where any intermediate ...
Arbieto, A., Oprocha, P., Rego, E.
openaire   +3 more sources

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source