Results 71 to 80 of about 2,402,993 (303)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Configuration of robust manufacturing systems [PDF]
, 2013 Considering the increasing turbulence in the markets, many companies are faced with the task of responding to changes in customer demand in a flexible and timely manner.
Heinicke, Matthias
core
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Body-worn and self-powered flexible optoelectronic device for metronomic photodynamic therapy
npj Flexible ElectronicsPhotodynamic therapy (PDT) as a clinical method relies on appropriate light delivery to activate photosensitizers, usually necessitates the utilization of cumbersome surgical instruments and high irradiation intensity, along with the requirement for ...
Jianhong Zhang +8 more
doaj +1 more source
Engineering ProceedingsThe fifth International Conference on the Challenges, Opportunities, Innovations, and Applications in Electronic Textiles (E-Textiles 2023) was held in Ghent (Belgium) on 14–16 November 2023.
Russel Torah +5 more
doaj +1 more source
A Reconfigurable Tile-Based Architecture to Compute FFT and FIR Functions in the Context of Software-Defined Radio [PDF]
, 2005 Software-defined radio (SDR) is the term used for flexible radio systems that can deal with multiple standards. For an efficient implementation, such systems require appropriate reconfigurable architectures.
Gerez, Sabih H. +3 more
core +2 more sources
A family of asymptotically stable control laws for flexible robots based on a passivity approach [PDF]
, 1991 A general family of asymptotically stabilizing control laws is introduced for a class of nonlinear Hamiltonian systems. The inherent passivity property of this class of systems and the Passivity Theorem are used to show the closed-loop input/output ...
Lanari, Leonardo, Wen, John T.
core +2 more sources
Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 2017 Under natural conditions, many aspects of the abiotic and biotic environment vary with time of day, season or even era, while these conditions are typically kept constant in laboratory settings. The timing information contained within the environment serves as critical timing cues for the internal biological timing system, but how this system drives ...
van der Veen, Daan R. +5 more
openaire +1 more source