Results 261 to 270 of about 112,673 (357)

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Temporary intraperitoneal breast implant spacer to facilitate safe stereotactic body radiotherapy for recurrent high-grade serous ovarian carcinoma. [PDF]

Gynecol Oncol Rep
Smith CE, Sandfeld EK, Cherian S, Rose PG.   +3 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

A Compliant SMA-Actuated Capsule Robot with Integrated Locomotion and Steering for Wireless Capsule Endoscopy. [PDF]

Micromachines (Basel)
Alshorman AM, Al-Zu'bi BS, Ababneh OA, Al Manasra AR, Alshurman K, Alhmoud T.   +5 more
europepmc   +1 more source

Investigation of prestressed concrete for highway bridges: Part I strength in shear of beams without web reinforcement [PDF]

, 1959
Siess, Chester Paul, 1916-, Sozen, Mete Avni, 1930-, Zwoyer, E.M.   +2 more
core  

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Idiopathic Duodenocolic Fistula Presenting as Chronic Diarrhea: Successful Surgical Management After Failed Endoscopic Closure. [PDF]

Cureus
Vieira B, Monteiro A, Pinto-de-Sousa J.
europepmc   +1 more source

Flexure of a slab on an elastic foundation

, 1959
Geoffrey Bosson
openalex   +2 more sources

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Incidental Diagnosis of Cholecystocolonic Fistula in An Asymptomatic Male: A Rare Case Presentation. [PDF]

Cureus
Bais N, Harris K, Bais S, Hamdani SU.
europepmc   +1 more source