Results 31 to 40 of about 17,182 (263)
Journal of Daylighting, 2021 Building owners are transitioning towards a smart lighting solution for illumination purposes. LED (Light Emitting Diode) lighting application has become a norm given its high efficacy and energy efficiencies.
Sivachandran R. Perumal, Faizal Baharum
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Brain InformaticsThe flicker stimulus is a visual stimulus of intermittent illumination. A flicker stimulus can appear flickering or steady to a human subject, depending on the physical parameters associated with the stimulus.
Keerthi S. Chandran, Kuntal Ghosh
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Sensory dynamics of visual hallucinations in the normal population
eLife, 2016 Hallucinations occur in both normal and clinical populations. Due to their unpredictability and complexity, the mechanisms underlying hallucinations remain largely untested.
Joel Pearson +5 more
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Improving Flicker of Low-Refresh-Rate Driven Active-Matrix Organic Light-Emitting Diode Display
IEEE Access, 2022 The brightness of low-temperature polycrystalline silicon and metal-oxide (LTPO) active-matrix organic light-emitting diode (AMOLED) display under low-refresh-rate driving condition tends to increase during pixel voltage holding time of each frame even ...
Kook Chul Moon +4 more
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FEBS Open Bio, EarlyView.NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce +72 more
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