Results 31 to 40 of about 1,540 (164)

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Distinguishing Hemodynamics from Function in the Human LGN Using a Temporal Response Model

open access: yesVision, 2019
We developed a temporal population receptive field model to differentiate the neural and hemodynamic response functions (HRF) in the human lateral geniculate nucleus (LGN).
Kevin DeSimone, Keith A. Schneider
doaj   +1 more source

“Low‐Positive” MOG‐IgG Cases Among Adults With a First Event Suggestive of Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the prevalence and clinical characteristics of patients with “low‐positive” (LP) MOG‐IgG (titres 1:160–1:320) among adults with a first demyelinating event (FDE) suggestive of multiple sclerosis (MS). Methods From the Barcelona CIS inception cohort, we included adult patients with serum collected ≤ 6 months from the FDE.
Javier Villacieros‐Álvarez   +29 more
wiley   +1 more source

Simulation of flicker noise

open access: yes四川大学学报. 自然科学版, 2016
Flicker noise is a widespread natural phenomenon, although its formation mechanism has not yet conclusive, it is very determined that the flicker noise power spectrum have f -a form.
Yan Gang-Feng, Guo Bing, Fang Hong
doaj  

Flicker minimization in power-saving displays enabled by measurement of difference in flexoelectric coefficients and displacement-current in positive dielectric anisotropy liquid crystals

open access: yesOpto-Electronic Advances
Balancing high display performance with energy efficiency is crucial for global sustainability. Lowering operating frequencies—such as enabling 1 Hz operation in fringe-field switching (FFS) liquid crystal displays—reduces power consumption but is ...
Junho Jung   +12 more
doaj   +1 more source

A Brücke–Bartley effect for contrast [PDF]

open access: yesRoyal Society Open Science, 2018
Accurate derivation of the psychophysical (a.k.a. transducer) function from just-notable differences requires accurate knowledge of the relationship between the mean and variance of apparent intensities.
Joshua A. Solomon   +1 more
doaj   +1 more source

The Development of Rheumatoid Arthritis–Specific Ambulatory Care–Sensitive Conditions: Results of a Consensus Process

open access: yesArthritis Care &Research, EarlyView.
Objective Ambulatory care–sensitive conditions (ACSCs) serve as indicators of access, quality, and performance of the health system. This study aimed to determine rheumatoid arthritis (RA)‐specific ACSCs for use in the evaluation of care system access and quality.
Kara Irwin   +7 more
wiley   +1 more source

A Cerebral Basis for Visual Discomfort and Visual Stress

open access: yesVision
Visual discomfort or visual stress is an uncomfortable subjective experience that occurs in response to specific visual stimuli. It affects a large proportion of the population to various degrees, disproportionately impacting those with heightened ...
Paul B. Hibbard   +31 more
doaj   +1 more source

Effects of the Photovoltaic Distributed Generation on Electricity Distribution System Voltage - Updated Review

open access: yesBrazilian Archives of Biology and Technology, 2018
Concerns about the environment and a growing demand for electricity have led to the intensive search for renewable energy sources. Photovoltaic solar energy, in the form of distributed generation, has shown a very high growth rate to an extent that in ...
Celso Fabrício Melo Júnior   +2 more
doaj   +1 more source

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