Results 111 to 120 of about 17,166 (262)

Rewiring NADH Metabolism Through NQO1‐Mediated Redox Cycling for Targeted Follicular Lymphoma Therapy

Advanced Science, EarlyView.
ABSTRACT Follicular lymphoma (FL) remains an incurable B‐cell malignancy with high relapse rates, and conventional therapies are often limited by significant toxicity, highlighting the need for novel treatments. We identified that FL exhibits markedly low expression of NAD(P)H: quinone oxidoreductase 1 (NQO1), a key enzyme required for activating ...
Jinxing Zhang, Ziqi Wang, Ye Weng, Yulin Fu, Yuelong Jiang, Beilin Zhuang, Wenzi Zeng, Xiangchun Zhang, Bing Xu, Jie Zha, Hongjun Zhuang   +10 more
wiley   +1 more source

Phase‐Resolved Defect Transport Mechanisms Governing Asynchronous Ordering in a Eutectic High‐Entropy Alloy

Advanced Science, EarlyView.
Phase‐resolved experiments and atomistic simulations reveal asynchronous ordering behaviors in a eutectic high‐entropy alloy during isothermal annealing. Distinct defect transport mechanisms are identified in coexisting B2 and BCC phases, showing that vacancy and interstitial mediated diffusion governs phase‐dependent thermal stability.
Huiwen Yao, Qingshuang Ma, Jie Xiong, Jing Bai, Huijun Li, Qiuzhi Gao   +5 more
wiley   +1 more source

Mechanism‐Informed Machine Learning Enables Discovery of Oncolytic Peptides for Cancer Immunotherapy

Advanced Science, EarlyView.
MISPOP integrates ensemble learning with membrane‐active physicochemical priors to identify Dermaseptin‐S9, a natural oncolytic peptide that disrupts tumor membranes, triggers immunogenic cell death, and shows strong antitumor activity. The study illustrates a mechanism‐informed route from peptide sequence data to cancer immunotherapy leads.
Wen Zhang, Shengxin Lu, Guangyong Zheng, Shensuo Li, Hongyu Chen, Mei Hong, Xiangru Zhou, Ruotian Tang, Ye Wu, Weidong Zhang, Dong Lu, Xin Luan   +11 more
wiley   +1 more source

40 Hz audiovisual stimulation improves sustained attention and related brain oscillations. [PDF]

Imaging Neurosci (Camb)
Attokaren MK, Zhang L, Mettupalli S, Singer AC.   +3 more
europepmc   +1 more source

Flexoelectricity in Photoconversion: Fundamentals, Materials, and Outlooks

Advanced Science, EarlyView.
Mechanical bending of a flexible cantilever induces a strain gradient in the photoactive material. The resulting flexoelectric field couples with photovoltaic and photoconductive effects, modulating charge generation, separation, and collection. A comparative analysis of oxide perovskites, halide perovskites, and two‐dimensional materials is presented,
Xiang Huang, Feng Li, Rongkun Zheng
wiley   +1 more source

Text Sequence Stimulation for High-Speed and Comfortable SSVEP-BCI. [PDF]

Cyborg Bionic Syst
Li X, Zhang S, Song Y, Zhang S, Chen X, Wang Y, Gao X.   +6 more
europepmc   +1 more source

Wide Temperature Zero Thermal Expansion in Al Matrix Composites with High Thermal Conductivity

Advanced Science, EarlyView.
Strain engineering strategy is implemented on the negative thermal expansion (NTE) phase Zn1.6Mg0.4P2O7 within composites, where Al matrix‐induced compressive strain drives uniform polyhedral and unit cell evolution, thereby enabling broad and consistent thermal compensation efficacy and obtaining good thermal performance.
Jinrui Qian, Feixiang Long, Yiqing Liu, Longlong Fan, Mingqing Liao, Qilong Gao, Hao Lu, Dexiang Gao, Le Kang, Yuzhu Song, Xiuzhu Han, Yue Sun, Naike Shi, Chang Zhou, Jun Chen   +14 more
wiley   +1 more source

Factors underlying flicker-induced time dilation: Temporal frequency, semantic content, and subjective saliency of visual stimuli. [PDF]

J Vis
Oda T, Houshmand Chatroudi A, Yotsumoto Y.   +2 more
europepmc   +1 more source

Multifaceted Roles of Tantalum in Promoting the Thermoelectric Performance of Mg3(Sb,Bi)2 Based Materials

Advanced Science, EarlyView.
A multifunctional tantalum incorporation strategy enables simultaneous tuning of carrier concentration, mitigation of grain‐boundary scattering, and enhanced phonon scattering in Mg3(Sb,Bi)2. These synergistic effects markedly improve carrier mobility and suppress lattice thermal conductivity, yielding both high material zT and high module conversion ...
Guangmeng You, Jingdan Lei, Kai Xu, Yuntian Fu, Xueke Gu, Chengxiao Peng, Zhen Wang, Jing Chen, Kunpeng Zhao, Chao Wang   +9 more
wiley   +1 more source

Rhythmic visual stimulation enhances visual search via occipito-parietal alpha modulation: an electroencephalographic study. [PDF]

Front Neurosci
Wang H, Bao S, Gang Z, Gao B, Fu W, Chi Y, Zhang M, Wu Y, Wu H, Niu H, Zhang C, Xu D, Shao Y, Xing W.   +13 more
europepmc   +1 more source