Results 41 to 50 of about 18,209,815 (307)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Energy-oriented architecture optimization method for aircraft

Hangkong gongcheng jinzhan
Multi-electric/all-electric flight vehicles usually face problems such as the complexity of coupling between systems, the overall energy efficiency and the economic balance. An energy-optimal architecture optimization method for aircraft is proposed.
SONG Yichuan, QIAO Fuxiang, LUO Yige, ZHANG Wenqian, ZHOU Cheng   +4 more
doaj   +1 more source

Guidance-Error-Based Robust Fuzzy Adaptive Control for Bottom Following of a Flight-Style AUV With Saturated Actuator Dynamics

IEEE Transactions on Cybernetics, 2020
This paper addresses the problem of robust bottom following control for a flight-style autonomous underwater vehicle (AUV) subject to system uncertainties, actuator dynamics, and input saturation.
Caoyang Yu, Xianbo Xiang, P. Wilson, Qin Zhang   +3 more
semanticscholar   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Whole-Body Offline-to-Online Planning for Robust Jumping of Full-Sized Humanoid Robot

Biomimetics
Dynamic bipedal jumping is highly sensitive to takeoff momentum and landing configuration, making the direct execution of purely offline-optimized trajectories unreliable on full-sized humanoid robots in the presence of modeling inaccuracies and ...
Weiping Yang, Wei Zhang, Qiang Tang, Hongyang Liu, Kexin Dang, Shanchao Yan, Mingguo Zhao, Bonan Yuan   +7 more
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

On inertial navigation and attitude initialization in polar areas

Satellite Navigation, 2020
Inertial navigation and attitude initialization in polar areas become a hot topic in recent years in the navigation community, as the widely-used navigation mechanization of the local level frame encounters the inherent singularity when the latitude ...
Yuanxin Wu, Chao He, Gang Liu
doaj   +1 more source

Research on automatic pilot repetition generation method based on deep reinforcement learning

Frontiers in Neurorobotics, 2023
Using computers to replace pilot seats in air traffic control (ATC) simulators is an effective way to improve controller training efficiency and reduce training costs.
Weijun Pan, Peiyuan Jiang, Yukun Li, Zhuang Wang, Junxiang Huang   +4 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source