Results 121 to 130 of about 589,125 (300)

Embedded CRISPRi Enhances Gene‐Silencing Efficiency in Drosophila

open access: yesAdvanced Science, EarlyView.
Current CRISPR interference (CRISPRi) technology in Drosophila has limited efficiency. This study introduces the emCRISPRi platform, which significantly enhances transcriptional silencing efficacy by embedding inhibitory domains within the dCas9 architecture.
Pengchong Fu   +7 more
wiley   +1 more source

A Testis‐Specific Aralkylamine N‐Acetyltransferase Regulates Dimorphic Sperm Function and Male Fertility in Moths

open access: yesAdvanced Science, EarlyView.
We identify a Lepidoptera‐conserved testis‐specific arylalkylamine N‐acetyltransferase (LTNAT) that governs male moth fertility via a novel mechanism. LTNAT loss disrupts eupyrene sperm mitochondrial derivatives and impairs apyrene sperm motility, offering a safe molecular target for innovative pesticides and genetic pest control.
Hao Sun   +5 more
wiley   +1 more source

Unemployment in Latin America and the Caribbean [PDF]

open access: yes
This study constructs a new data set on unemployment rates in Latin America and the Caribbean and then explores the determinants of unemployment. We compare different countries, finding that unemployment is influenced by the size of the rural population ...
Laurence Ball   +2 more
core   +3 more sources

Hijacking the Host Clock: A Nematode Effector Antagonizes Soybean Circadian Defense and Translation Control

open access: yesAdvanced Science, EarlyView.
Soybean employs its circadian clock, governed by GmCCA1, to rhythmically defend against soybean cyst nematodes. The pathogen retaliates by secreting the effector Hg4E02, which hijacks the clock to suppress defense and co‐opt the host's translation machinery for nutrient acquisition.
Xingwei Wang   +21 more
wiley   +1 more source

The catch of tortricid moths to pheromone traps in apple orchards. Part I. Dynamics of moths flight

open access: yesAnnales Horticulturae, 2015
The studies were conducted in three apple orchards in the Lublin province in the years 1999–2001. Their purpose was to establish the flight dynamics of three species of leaf tortricids (Spilonota ocellana, Pandemis cerasana, Archips podana) on the basis ...
IZABELA KOT
doaj  

Effectively Transforming IMC Flight into VMC Flight: An SVS Case Study [PDF]

open access: yes, 2006
A flight-test experiment was conducted using the NASA LaRC Cessna 206 aircraft. Four primary flight and navigation display concepts, including baseline and Synthetic Vision System (SVS) concepts, were evaluated in the local area of Roanoke Virginia ...
Glaab, Louis J.   +3 more
core   +1 more source

Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next‐Generation Approaches

open access: yesAdvanced Science, EarlyView.
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey   +6 more
wiley   +1 more source

Feature discrimination/identification based upon SAR return variations [PDF]

open access: yes
A study of the statistics of The look-to-look variation statistics in the returns recorded in-flight by a digital, realtime SAR system are analyzed.
Pietsch, R., Rasco, W. A., Sr.
core   +1 more source

Disruption of Treg Homeostasis in Rheumatoid Arthritis via Ferroptosis‐Mediated ETC Collapse and TXK‐STAT3/PLCγ1 Activation

open access: yesAdvanced Science, EarlyView.
In rheumatoid arthritis, synovial Tregs accumulate but are functionally impaired due to iron overload‐induced ferroptosis. This triggers mitochondrial dysfunction and TXK tyrosine kinase‐mediated signaling, leading to Treg destabilization and inflammation.
Jingrong Chen   +19 more
wiley   +1 more source

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