Results 51 to 60 of about 589,125 (300)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The Adaptability of Beet Webworm (Loxostege sticticalis) to Soybeans and Other Different Host Plants

Agronomy
The beet webworm Loxostege sticticalis has caused significant economic losses to the production of agriculture and animal husbandry in China. Preference testing of larva feeding and adult oviposition and flight capability tests were carried out on five ...
Xingwei Ji, Xingfu Jiang, Jiao Yin, Julian Chen, Tianbo Ding, Xiaoling Tan   +5 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Discrimination, labour markets and the Labour Market Prospects of Older Workers: What Can a Legal Case Teach us? [PDF]

, 2007
As governments become increasingly concerned about the fiscal implications of the ageing population, labour market policies have sought to encourage mature workers to remain in the labour force.
Blake Dawson Waldon, Bowles, S., Cota, Encel, S., Gordon, D.M., Harris, C.C., Hochschild, A.R., Hreoc, Long, S., McDowell, L., McKeown, T., Murtough, G., Pickersgill, R., Pissarides, C.A., Rubery, J., Sally A. Weller, Samson, A., Savage, D., Virgin Airlines, Von Kries, J., Webber, M.J., Weller, S.A., White, L.   +22 more
core   +1 more source

Feasibility and Tolerability of Performing Portable MRI for Neurological Disorders in an Outpatient Neurology Clinic: A Prospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick, Nomin Enkhtsetseg, Joseph Sadok, Matheus Mochetti, Annabel Sorby Adams, Jennifer Guo, Cristina Trapaga Hacker, Isabella Gomez Hjerthen, Seungwon Lee, Siddharth Satish, Andrew S. Ham, Justin Hill, Denis Balaban, Kevin Kyle, Rebecca L. Gillani, Marcelo Matiello, Aleksandar Videnovic, Eric C. Klawiter, W. Taylor Kimberly, Farrah J. Mateen   +19 more
wiley   +1 more source

Phenotypic variability in traits related to flight dispersal in the wing dimorphic species Triatoma guasayana

Parasites & Vectors, 2023
Background Triatoma guasayana is considered an emerging vector of Chagas disease in the Southern Cone of South America. The presence of a triatomine population with brachypterous individuals, in which both wings are reduced, has recently been reported ...
Gisel V. Gigena, Claudia S. Rodríguez, Federico G. Fiad, María Laura Hernández, Ana Laura Carbajal-de-la-Fuente, Romina V. Piccinali, Paz Sánchez Casaccia, Antonieta Rojas de Arias, Patricia Lobbia, Luciana Abrahan, Marinely Bustamante Gomez, Jorge Espinoza, Florencia Cano, Julieta Nattero   +13 more
doaj   +1 more source

Slingshot Dynamics for Self Replicating Probes and the Effect on Exploration Timescales [PDF]

, 2013
Interstellar probes can carry out slingshot manoeuvres around the stars they visit, gaining a boost in velocity by extracting energy from the star's motion around the Galactic Centre. These maneouvres carry little to no extra energy cost, and in previous
Forgan, Duncan, Nicholson, Arwen
core   +1 more source

Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli, Mudasir Andrabi, Tova Cohen, Pranali G. Patel, Tapasya Katta, Chen Lin   +5 more
wiley   +1 more source

Aseasonal, undirected migration in insects: 'Invisible' but common

iScience
Summary: Many insect pests are long-distance migrants, moving from lower latitudes where they overwinter to higher latitudes in spring to exploit superabundant, but seasonally ephemeral, host crops.
Thomas W. Sappington
doaj   +1 more source

Comparison of Reproductive and Flight Capacity of Loxostege sticticalis (Lepidoptera: Pyralidae), Developing From Diapause and Non-Diapause Larvae [PDF]

, 2012
The beet webworm, Loxostege sticticalis (L.) (Lepidoptera: Pyralidae), uses both diapause and migration as life history strategies. To determine the role of diapause plays in the population dynamics of L.
Jiang, Xingfu, Luo, Lizhi, Sappington, Thomas, Sappington, Thomas, Xie, Daosong, Zhang, Lei   +5 more
core   +3 more sources