SUMOylation, a dynamic post‐translational modification, acts as a master regulator at the heart of tumor malignancy. Our work delineates how the SUMOylation cycle—mediated by E1/E2/E3 enzymes and reversed by SENPs—orchestrates multiple hallmarks of cancer. The central pathway converges on three critical pathological axes: 1.
Yimao Wu +6 more
wiley +1 more source
WISeRKNet: wide slice residual Kronecker network for lung cancer detection based on CT images. [PDF]
Shanthi A, Satheesh Kumar S, Koppu S.
europepmc +1 more source
A MR Fingerprinting Development Kit for Quantitative 3D Brain Imaging
ABSTRACT Background Magnetic resonance fingerprinting (MRF) is an emerging quantitative imaging technique that enables multiparametric tissue characterization, but its adoption has been hindered by the complexity of data acquisition and post‐processing. These technical and implementation challenges have limited its broader clinical deployment.
Rasim Boyacioglu +11 more
wiley +1 more source
Explaining attractive and repulsive biases in the subjective visual vertical. [PDF]
Glasauer S, Medendorp WP.
europepmc +1 more source
ABSTRACT Background The impact of deep learning (DL) reconstruction and segmentation on MRI radiomics stability has not been fully assessed. Purpose To investigate the effects of acquisition, reconstruction, and segmentation on the reproducibility and variability of radiomic features in abdominal MRI. Study Type Prospective.
Jingyu Zhong +14 more
wiley +1 more source
Prevalence of self-reported symptoms of reproductive tract infections and promoting an awareness of reproductive health among adolescent girls through education approach in Kumbakonam rural region of Tamil Nadu state. [PDF]
Balamurugan PP, Praveen V, Kolli B.
europepmc +1 more source
Characterization of Pulmonary Functional Abnormalities in Systemic Sclerosis Using Xenon MRI
ABSTRACT Background Xenon MRI is increasingly used to evaluate patients with interstitial lung disease (ILD) and pulmonary hypertension (PH), both of which are common manifestations of systemic sclerosis (SSc). As such, Xe‐MRI may be suited to interrogate lung function impairment in SSc.
Dawson Shaver +11 more
wiley +1 more source
Postexercise Lactate Clearance, T<sub>2</sub> Relaxation, and J-Modulation in Human Skeletal Muscle Measured With Double-Quantum Filtered <sup>1</sup>H MRS at 7 T. [PDF]
Repnin K +6 more
europepmc +1 more source
ꟻLIP‐Based Perceptual Optimization for Subpixel Rendering Filters
We propose a two‐stage subpixel rendering framework combining MMSE‐based initialization and ꟻLIP‐guided perceptual optimization. The kernel is refined by minimizing the mean ꟻLIP error using a Nelder‐Mead optimizer to reduce perceptual distortion beyond RGB‐based methods.
Bo‐Jyun Chen +4 more
wiley +1 more source

