Results 31 to 40 of about 179,987 (217)

Development of sustained-release floating tablets of diltiazem hydrochloride

open access: yesVietnam Journal of Science, Technology and Engineering
Diltiazem hydrochloride (DTZ), utilised for cardiovascular conditions, possesses a short half-life, necessitating frequent dosing. To enhance compliance, sustainedrelease (SR) floating tablets were developed using a Quality by Design (QbD) approach ...
Hung Pham Van   +5 more
doaj   +3 more sources

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Research of Non-metallic Inclusions Removal in Teeming Ladles of Various Design

open access: yesЖурнал інженерних наук, 2018
It was studied in the article the possibility of intensification of removal of non-metallic inclusions in a teeming ladle during holding without any additional external influences on the metal (argon blowing or electromagnetic stirring).
Molchanov L. S.   +3 more
doaj   +1 more source

Performance Evaluation Of Floating Solar Power Plant In Sidobandung Bojonegoro

open access: yesThe Spirit of Society Journal: International Journal of Society Development and Engagement, 2023
Sidobandung Village is a village that will develop the potential of the village as a tourism village.The Solar Power Generation System is a power generation equipment.
Mohammad Basuki Rahmat   +5 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

FLOATING GASTRO-RETENTIVE DOSAGE FORMS - A NOVEL APPROACH FOR TARGETED AND CONTROLLED DRUG DELIVERY

open access: yesHuman Research in Rehabilitation, 2012
Controlled (modified) release dosage forms are one of the key concepts in drug delivery, leading to enhanced drug bioavailability and increased patient’s compliance.
Aleksandar Aleksovski
doaj   +2 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Hydraulic Experiments on a Small-Scale Wave Energy Converter with an Unconventional Dummy Pto

open access: yesEnergies, 2019
This paper investigates on a Wave Energy Converter (WEC) named Energy & Protection, 4th generation (EP4). The WEC couples the energy harvesting function with the purpose of protecting the coast from erosion.
Luca Martinelli   +3 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

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