Results 61 to 70 of about 179,987 (217)

FORMULATION AND EVALUATION OF EFFERVESCENT GASTRO-RETENTIVE FLOATING TABLETS FOR CONTROLLED RELEASE OF AN ANTI-ULCER COMPOUND

open access: yesHuman Research in Rehabilitation, 2013
Effervescent floating gastro-retentive matrix tablets present novel and promising approach towards targeted and controlled drug delivery in the stomach and in the upper part of the small intestine.
Aleksandar Aleksovski   +3 more
doaj  

Communication on the potential of applied PV in the European Union: Rooftops, reservoirs, roads (R3)

open access: yesEPJ Photovoltaics
Photovoltaics (PV) is a cost-competitive and scalable technology for electricity generation that plays a crucial role to accelerate the European energy transition and achieve carbon neutrality.
Kakoulaki Georgia   +5 more
doaj   +1 more source

Il futuro regime dei tassi di cambio.

open access: yesMoneta e Credito, 2014
When the Committee of Twenty decided to rename the exchange-rate regime rather than reform it, some two weeks after the system had collapsed, it immediately became clear that the ambitious attempt to write a new monetary constitution for the world had ...
J. WILLIAMSON
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

The future exchange rate regime

open access: yesPSL Quarterly Review, 2014
When the Committee of Twenty decided to rename the exchange-rate regime rather than reform it, some two weeks after the system had collapsed, it immediately became clear that the ambitious attempt to write a new monetary constitution for the world had ...
J. WILLIAMSON
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Resilient Waterfront Futures: Mapping Vulnerabilities and Designing Floating Urban Models for Flood Adaptation on the Tiber Delta

open access: yesLand
This paper explores the feasibility of floating urban development in Italy, given its extensive coastline and inland hydrographic network. The key drivers for floating urban development, as an adaptive approach in low-lying waterfront areas, include the ...
Livia Calcagni   +2 more
doaj   +1 more source

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