Results 131 to 140 of about 5,721,777 (374)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Design and Construction of Spud Housing for Floating Dock

MATEC Web of Conferences, 2018
A floating dock is a type of pontoon for dry docking ships, possessing floodable buoyancy chambers. The Floating docks have more advantages than the other type of ship docking for maintenance.
Hasanudin Hasanudin, Yulianto Ardi Nugroho   +1 more
doaj   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

A comparison of floating point summation methods [PDF]

, 1972
James Philip Gregory
openalex   +1 more source

A Latency-Effective Pipelined Divider for Double-Precision Floating-Point Numbers [PDF]

, 2020
Juwon Yun, Jinyoung Lee, Woonam Chung, Cheong Ghil Kim, Woo-Chan Park   +4 more
openalex   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Very-Large-Scale Integration (VLSI) Implementation and Performance Comparison of Multiplier Topologies for Fixed- and Floating-Point Numbers

Applied Sciences
Multiplication is an arithmetic operation that has a significant impact on the performance of several real-life applications such as digital signals, image processing, and machine learning.
Abimael Jiménez, Antonio Muñoz
doaj   +1 more source

Performance of FORTRAN floating-point operations on the Flex/32 multicomputer [PDF]

A series of experiments has been run to examine the floating-point performance of FORTRAN programs on the Flex/32 (Trademark) computer. The experiments are described, and the timing results are presented.
Crockett, Thomas W.
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

No Multiplication? No Floating Point? No Problem! Training Networks for Efficient Inference [PDF]

, 2018
Shumeet Baluja, David Marwood, Michele Covell, Nick Johnston   +3 more
openalex   +1 more source